Browsing by Title
Now showing items 15481-15500 of 17713
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(2021-03-06)Department: ChemistryUmpolung amide synthesis (UmAS) exploits the unique properties of an α-halo nitroalkane in its reaction with an amine to produce an amide. The “umpolung” moniker reflects its paradigm-breaking C–N bond formation on the ...
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(2014-07-22)Department: ChemistryTraditional amide synthesis employs a nucleophilic amine, which is reacted with an electrophilic activated carboxylic acid or carboxylic acid surrogate. Recently, colleagues in the Johnston lab introduced an unconventional ...
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(2012-12-03)Department: ChemistryUMPOLUNG AMIDE SYNTHESIS: APPLICATIONS IN ENANTIOSELECTIVE PEPTIDE SYNTHESISDAWN M. MAKLEYDissertation under the direction of Professor Jeffrey N. JohnstonThe development and application of the novel Umpolung Amide Synthesis ...
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(Asociación Canadiense de Hispanistas, 2007)A pesar de la creciente ubicuidad de la tecnología digital, la crítica literaria apenas ha explorado de manera práctica las posibilidades expositivas del hipertexto cibernético, especialmente en lo que hace a la utilización ...
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(2021-06-15)Department: FrenchIn this dissertation, close readings of twenty-first century texts by Annie Ernaux, Nina Bouraoui, Maïssa Bey and Chloé Delaume expose the role of language and the possibilities offered by autofictional space in the ...
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(2021-03-24)Department: SociologyUnequal access to important resources in the urban built environment has been a significant social problem under study by social scientists. Guided by an environmental justice framework, this mixed-method dissertation takes ...
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(Vanderbilt University. Writing Studio, 2009-03-22)
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(Center for American Progress, 2014)Since the 2008 financial crisis, the problem of financial institutions being "too big to fail," or TBTF, has been front and center in the public debate over the reform and regulation of the financial industry. Commentators ...
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(2010-03-18)Department: Cell and Developmental BiologyCoordinated movement depends on specific connections between neurons, yet mechanisms that govern synaptic specificity are poorly understood. The simple, well-defined motor circuit of the nematode, C. elegans provides an ...
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(2017-09-08)Department: Civil EngineeringProbabilistic performance assessment evaluates a system’s capability to accomplish the required functions under uncertainty. The results of probabilistic performance assessment can be used to support decision making such ...
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(2008-04-11)Department: Mechanical EngineeringModeling and simulation have played an increasingly important role in the design and analysis of engineering systems. High-consequence decisions are often informed strongly by numerical results obtained through the use ...
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(2022-08-04)Department: PsychologyIntolerance of uncertainty (IU) is the tendency to react negatively to uncertain situations due to negative beliefs about uncertainty. IU demonstrates robust associations with symptoms of obsessive-compulsive disorder ...
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(2015-11-27)Department: Biomedical EngineeringImage-guided surgical methods have been investigated as techniques to increase the localization accuracy of hepatic cancer treatments such as resection and ablation. Mathematical registration methods are currently used to ...
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(2017-07-31)Department: Civil EngineeringMultidisciplinary simulations are often assembled based on limited data and approximate individual and partial-physics model components. Methodologies are proposed to address the following three challenges in the context ...
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Uncertainty Quantification and Decision Making in Hierarchical Development of Computational Models (2009-07-27)Department: Civil EngineeringAs engineering systems grow in size and complexity, it is becoming increasingly difficult to assess their performance through full scale testing. Modeling and simulation fill the gap left by the lack of full scale testing ...
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(2012-02-16)Department: Civil EngineeringA comprehensive framework for the treatment of uncertainty is essential to facilitate decision-making in engineering systems at every stage of the life cycle, such as design, manufacturing/construction, operations, system ...
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(2020-01-14)Department: Civil EngineeringAdditive manufacturing (AM) has shown immense potential in several industries. However, significant variability in the product quality currently hinders widespread use of AM. The focus of this dissertation is on uncertainty ...
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(2021-01-13)Department: Civil EngineeringThis dissertation is concerned with understanding the uncertainty and variability in the failure and nonlinear response of materials with heterogeneous microstructures at fine scales (i.e., micrometers to millimeters). In ...
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(2010-08-11)Department: Civil EngineeringFatigue crack growth is a stochastic process and different kinds of uncertainty – physical variability, data uncertainty and modeling errors – should be included within the analysis to more accurately represent the fatigue ...
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(2013-09-19)Department: Civil EngineeringThe prediction of failure probability for engineering components/devices under service conditions often involves the use of predictive models and measurement data. The fact that no model is absolutely correct indicates the ...