Browsing by Subject "obesity"
Now showing items 21-28 of 28
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(2014-07-25)Department: Molecular Physiology and BiophysicsLoss-of-function mutations causing haploinsufficiency of the MC4R are the most common monogenic cause of severe early-onset obesity in humans. Research has primarily focused on how central MC4R contributes to energy ...
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(2014-06-27)Department: Molecular Physiology and BiophysicsIn the past decade, evidence has emerged that obesity induces a neuroinflammatory response in the hypothalamus, a part of the brain that contains neuronal circuitry controlling feeding and metabolism. The potential ...
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(2013-04-11)Department: Molecular Physiology and BiophysicsObesity is a prevalent disorder that increases the risk of developing many metabolic diseases, including insulin resistance (IR) and type 2 diabetes. Research conducted in the past decade has shown that accumulation of ...
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(2017-12-12)Department: Molecular Physiology and BiophysicsObesity has reached epidemic proportions worldwide, with some of the greatest severity in the United States. The most recent data reports ~70% of the American population is overweight (BMI ≥ 25 kg/m2) and ~35% obese (BMI ...
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(2020-03-19)Department: Nursing ScienceBackground: Eating preferences and practices are established early in life, yet we have little knowledge about how mothers make food decisions on behalf of their children. These decisions, however, lay the foundation for ...
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(2010-08-04)Department: PharmacologyDopaminergic neurotransmission is a critical component in the regulation of several behaviors, including cognition, motor function, motivation, and reward. Abnormalities in dopamine (DA) signaling have been linked to ...
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(2009-12-11)Department: Molecular Physiology and BiophysicsObesity is a strong risk factor for type 2 diabetes and cardiovascular disease partly because of the changes that occur in white adipose tissue (WAT) during weight gain. As obesity progresses, WAT expands, becomes ...
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The Role of the Prostaglandin E2 EP3 Receptor in Obesity, Insulin Resistance, and Glycemic Control (2015-12-01)Department: PharmacologyMice carrying a targeted disruption of the prostaglandin E2 E-prostanoid receptor 3 (EP3) gene, Ptger3, were fed a high-fat diet (HFD), or a micronutrient matched control diet, to investigate the effects of disrupted ...