Browsing by Title
Now showing items 1398-1417 of 17382
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(Vanderbilt University, 2007-02-17)
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(2019-03-22)Department: Cell and Developmental BiologyThe basement membrane is a sheet-like extracellular matrix that wraps around muscle fibers and underlies epithelia. Although the basement membrane is often considered to be static, there are indications that the BM is a ...
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(2023-03-14)Department: BiochemistryType II topoisomerases are essential enzymes that regulate the topological state of DNA. These enzymes function by performing a double-stranded DNA passage reaction, the process of which generates a covalent enzyme-cleaved ...
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(Vanderbilt University. Peabody College, 2012-06-15)In the paper I explore some of the history of disengaged readers and segue into an exploration of the ways in which more recent literature discusses disengaged readers. I conclude with implications as to how the more recent ...
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(2012-11-05)Department: Biomedical InformaticsIn shotgun proteomics, database search algorithms rely on fragmentation models to predict fragment ions that should be observed for a given peptide sequence. The most widely used strategy (Naïve model) is oversimplified, ...
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(Vanderbilt University, 2007-08-30)
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(Chicago-Kent Law Review, 1998)The choice of whether to adopt or preserve judicial peremptories should not turn on the resolution of one issue. The risk that such challenges will be used to discriminate between judges on the basis of race must be ...
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(Environmental Law, 2004)The substantive contours of the Endangered Species Act (ESA) have been largely worked out for quite some time. Starting in the mid-1990s, however, opponents of Fish and Wildlife Service and National Marine Fisheries Service ...
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(2014-08-04)Department: HistoryThis paper employs the NAACP records, military records, oral histories, and newspapers to reconstruct the efforts of civil rights lawyer Thurgood Marshall and his NAACP colleagues to launch a full-scale investigation of ...
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(1860-01-01)
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(1860-01-01)
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(2020-11-18)Department: Civil EngineeringCritical infrastructure systems provide essential services that support modern society. However, these systems are deteriorating and becoming more vulnerable to multiple hazards. In order to improve their resilience (i.e., ...
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(2022-05-10)Department: BiostatisticsBayesian methods offer many advantages in clinical trials, healthcare evaluation, and drug development, but their usage lags that of classical 'frequentist' methods. While some of this lag is related to philosophical ...
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(2018-11-27)Department: BiostatisticsThis dissertation broadly focuses on the advancement and extension of Bayesian methods for multivariate survival analysis with applications in larger data settings. Increased sample information allows researchers to develop ...
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(2005-12-19)Department: Cancer BiologyCANCER BIOLOGY BCL-2/BCL-XL REGULATES CELL CYCLE THROUGH A NOVEL MECHANISM IN ADDITION TO CELL SURVIVAL YELENA MELKUM JANUMYAN Dissertation under the direction of Professor Elizabeth Yang Bcl-2 and Bcl-xL are ...
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(2011-12-09)Department: Chemical and Physical BiologyStructural information facilitates understanding of protein function and activity. The limitations of experimental methods for protein structure elucidation in applicability to certain types and families of proteins, ...
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(2016-03-28)Department: Biomedical InformaticsThe Biochemical Library (BCL) is a protein structure prediction algorithm developed in the Meiler Lab at Vanderbilt University based on the placement of secondary structure elements (SSEs). This algorithm incorporates ...