Browsing by Title
Now showing items 2374-2393 of 17412
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(2019-04-09)Department: Biomedical EngineeringOtitis media (OM), an inflammatory disease of the middle ear, is the most frequent cause of physician visits and prescription of antibiotics for children. Current methods to diagnose OM rely on varying symptoms and visual ...
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(2022-03-21)Department: Biological SciencesDNA is a fundamental biomolecule of life which stores the genetic information of organisms and drives many of the evolutionary processes in nature. Despite this, DNA is subject to physical and chemical damage from environmental ...
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(2022-03-21)Department: Biological SciencesDNA is a fundamental biomolecule of life which stores the genetic information of organisms and drives many of the evolutionary processes in nature. Despite this, DNA is subject to physical and chemical damage from environmental ...
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(2010-04-30)Department: Chemical and Physical BiologyIn this thesis, the structural differences between wild-type band 3 and band 3 Fukuoka, the G130R mutant identified in cases of hereditary spherocytosis associated with reduction of protein 4.2, are examined. The G130R ...
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(2023-07-17)Department: Biomedical EngineeringEndometriosis is a debilitating gynecological condition that afflicts more than 10% of reproductive-age women worldwide. It is characterized by the abnormal growth of endometrial tissue outside of the uterine cavity. Despite ...
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(2005-11-01)Department: Cell and Developmental BiologyThe work contained in this document provides the first description and characterization of Bves, a gene product identified by our laboratory, in epithelial cell types. Studies addressed a central hypothesis that Bves plays ...
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(2005-07-12)Department: Cell and Developmental BiologyThe study of cytokinesis in fission yeast S.pombe has revealed a signaling network, the septation initiation network (SIN) that serves to coordinate cytokinesis with mitotic exit in the fission yeast Schizosaccharomyces ...
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(2018-08-28)Department: Cell and Developmental BiologyCell division cycle 14 (Cdc14) is an evolutionarily conserved phosphatase originally identified in <em>Saccharomyces cerevisiae</em> as a cell cycle regulator. In <em>Drosophila melanogaster</em>, Cdc14 is encoded by a ...
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(2021-08-02)This paper explores the current and needed identities and competencies of a small but growing environmental nonprofit organization, the South Louisiana Wetlands Discovery Center. The current board is neither designed nor ...
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(2005-03-25)Department: Cell and Developmental BiologyLIS1 and NudE(L) are partner proteins in a conserved pathway regulating the function of dynein and microtubules. Members of the LIS1 pathway play a critical role in fundamental cellular processes, such as differentiation, ...
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(2017-10-20)Department: Microbiology and ImmunologyCytomegalovirus (CMV) infection or latency reactivation is usually asymptomatic except in immune-suppressed hosts where it causes end-organ complications. CMV has also been proposed to drive cardiovascular disease in ...
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(2011-07-26)Department: PathologyCharacterization of fibrinogen-binding surface protein B (FbsB) in human blood coagulation and fibrinolysis, and of the NH2-terminal dipeptide of staphylocoagulase (SC) in conformational prothrombin activation are presented ...
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Characterization of functional human antibodies targeting henipavirus and flavivirus glycoproteins (2021-06-14)Department: Microbe-Host InteractionsThe henipaviruses Hendra (HeV) and Nipah (NiV), and the flavivirus yellow fever (YFV), pose massive global public health threats. No small molecule or antibody-based countermeasures are available to treat humans infected ...
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(2017-10-04)Department: NeuroscienceEpileptic encephalopathies (EEs) are a devastating group of severe childhood onset epilepsies with medication resistant seizures and poor developmental outcomes. Many EEs have a genetic etiology and are often associated ...
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(2008-03-13)Department: Biological SciencesDopamine plays key roles in many basic functions in the central nervous system. In order to study developmental and functional roles of dopaminergic cells in the zebrafish, we have examined a transgenic line of zebrafish ...
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(2018-06-11)Department: Biological SciencesDNA glycosylases preserve genome integrity and define the specificity of the base excision repair pathway for discreet, detrimental modifications. Bacterial HEAT-like repeat glycosylases AlkC and AlkD are specific for ...
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(2014-05-13)Department: Electrical EngineeringSingle event transients (SET) have become increasingly important to characterize since operating frequencies have surpassed 100 MHz. A common way to characterize SETs for a specific technology is to measure the range of ...
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(2008-12-06)Department: Electrical EngineeringRadiation-induced soft errors have become a key reliability issue for advanced semiconductor integrated circuits. With technology scaling, a large fraction of the observed soft failures are estimated to be related to latched ...
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(2012-04-26)Department: PharmacologyProteostasis is maintained by a complex network of genes and processes which includes core synthesis and degradation machineries as well as chemical and protein chaperones. Much of what is known about the function and ...
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(2023-08-15)Department: NeuroscienceThe insular cortex (IC) integrates sensory and interoceptive cues to inform downstream circuitry executing adaptive behavioral responses. The IC communicates with areas involved canonically in stress and motivation. IC ...