Browsing by Title
Now showing items 2405-2424 of 17440
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(2021-12-06)Department: Electrical EngineeringDevice-level radiation-induced photocurrent measurements, for characterization purposes and use in radiation hardening by design (RHBD) techniques, have historically been performed through off-chip measurements of ...
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(2011-08-01)Department: ChemistryCharacterization of Post-Translationally Modified Peptides and Proteins Using Lanthanide-Based Labeling Strategies By Randi Gant-Branum Abstract: Numerous biological processes are regulated by the stoichiometry of protein ...
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(2023-03-24)Department: Electrical EngineeringThis research presents a methodology for on-chip measurement of transient photocurrent for technology characterization and mechanism discovery with implementation and demonstration in two sub-50nm silicon-on-insulator (SOI) ...
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(2008-07-27)Department: Biomedical EngineeringRaman spectroscopy has the potential for providing differential diagnosis between dysplasia and benign cervix with high sensitivity and specificity. Two in vivo studies where designed to further evaluate the potential and ...
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Characterization of Recent Evolutionary Signatures of Genetic Elements involved in Human Pregnancy (2019-05-08)Department: Biological SciencesEutherian pregnancy is characterized by relatively prolonged gestation and early establishment of direct maternal-fetal contact. In order to support extended growth of a genetically distinct fetus, the maternal immune ...
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(2013-12-02)Department: Earth and Environmental SciencesThis project attempts to identify the source of surface water and groundwater salinity observed in a polder in southwest Bangladesh through geochemical analyses. All surface water samples are mixtures of tidal channel ...
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(2014-07-28)Department: Electrical EngineeringThe response of electronic devices to ionizing radiation is a reliability concern for commercial and space applications. An ionizing particle can cause charge to be generated and collected at the node of a circuit. If the ...
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(2009-04-21)Department: Electrical EngineeringAs technology nodes scale smaller, digital circuits are able to run at higher clock frequencies, but they can become more susceptible to single-event induced errors. These types of errors can be generated in combinational ...
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Characterization of SRAP Domain DNA-Protein Crosslink Formation and Reversal with DNA Abasic Sites (2022-06-27)Department: BiochemistryApuirinic/apyrimidinic (AP, or abasic) sites in DNA are one of the most common forms of DNA damage. AP sites are reactive and form crosslinks to both proteins and DNA, are prone to strand breakage, and inhibit DNA replication ...
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(2005-04-06)Department: Cell and Developmental BiologyHypoxia inducible vascular endothelial growth factor (VEGF) plays a major role in initiation and regulation of retinal neovascularization, which is the leading cause of severe vision loss and irreversible blindness in ...
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(2014-08-15)Department: PathologyThe oncogenes Mdm2 and Mdmx are often overexpressed in many human cancers. In addition to being negative regulators of the tumor suppressor p53, there is evidence these proteins have important p53-independent functions ...
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(2018-11-27)Department: ChemistryAlkylating agents, once a weapon of war employed in World War I, are the oldest class of chemotherapeutic agents still used today, with applications in treating a wide array of cancers. Methylating agents, in particular, ...
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(2023-07-21)Department: Biomedical EngineeringTumor-induced bone disease (TIBD) is associated with severe morbidities and reduced survival rates in metastatic cancer patients. Gli2 transcription factor plays a critical role in bone metastasis and TIBD by promoting ...
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(2019-07-16)Department: PsychologyAcetylcholine (ACh) is a ubiquitous and well-studied neurotransmitter, best characterized in the peripheral nervous system where it acts as the signaling molecule at the neuromuscular junction. Despite being among the first ...
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(2018-04-02)Department: Electrical EngineeringWith technology scaling at 22 nm and beyond, the semiconductor industry has successfully transitioned to 3D multi-gate transistors (i.e., FinFETs) due to the excellent FinFET gate control and reduced short channel effects ...
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(2005-08-11)Department: Biological SciencesPSF (PTB-associated splicing factor) has been implicated in both early and late steps of pre-mRNA splicing as well as multiple nuclear events including transcription regulation, nuclear RNA retention/export, topoisomerase ...
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(2009-06-15)Department: Molecular Physiology and BiophysicsThe bed nucleus of the stria terminalis (BNST) is a region of the brain critical in mediating behavioral and physiological responses to stress and anxiety. Stress is a major cause of relapse for drug addicts attempting ...
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(2022-07-20)Department: Microbe-Host InteractionsHantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact. While sporadic in North and South America, many infections ...
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(2012-04-09)Department: Electrical EngineeringAs transistor density increases with each new CMOS technology node, the probability of a single ion causing a single-event transient in a circuit or inducing charge sharing among transistors increases. These transients can ...
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(2014-07-28)Department: Cell and Developmental BiologyThe apical recycling endosome supported by myosin Vb (MYO5B) acts as the main decision point for both the biosynthetic and endocytic pathways as they traffic proteins to and from the apical surface in polarized cells. ...