Browsing by Title
Now showing items 7116-7135 of 17440
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(19 Interdisciplinary Studies in the Long Nineteenth Century, 2008-10)The Legacy of Cain (1888), the last novel Wilkie Collins published before his death, is structured as a case study of the respective influences of nature and nurture. The central question is whether the daughter of a ...
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(2012-07-19)Department: PsychologyCognitive dysfunction is a core feature of schizophrenia, but the precise nature of these deficits has yet to be delineated. The goal of the following series of experiments was to advance our understanding of two particular ...
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(2018-08-30)Department: NeuroscienceInhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice Victoria S. Cavener Dissertation under direction of Professor Sachin Patel Elucidating the underlying molecular mechanisms regulating fear and extinction ...
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(2016-07-27)Department: Biological SciencesRetina damage or disease in humans often leads to reactive gliosis, preventing the formation of new cells and resulting in visual impairment or blindness. Currently, treatments are being developed to stimulate repair or ...
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(2020-07-20)Department: BiochemistryChromatin-modifying enzymes have been identified as promising therapeutic targets for a variety of malignancies. One such target is the histone demethylase Lysine-Specific Demethylase 1 (LSD1), which is found in transcriptional ...
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(Nature Communications, 2019-05-01)SMARCB1 encodes the SNF5 subunit of the SWI/SNF chromatin remodeler. SNF5 also interacts with the oncoprotein transcription factor MYC and is proposed to stimulate MYC activity. The concept that SNF5 is a coactivator for ...
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(2017-12-05)Department: Microbiology and ImmunologyThe host protein cyclophilin A (CypA) can both stimulate and inhibit HIV-1 infection through its interaction with the viral capsid (CA). CypA enhances the early stages of HIV-1 infection in part by promoting nuclear import ...
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(2023-04-21)Tactile symbols are often used as a form of communication for students with complex support needs, specifically those that have comorbidity of blindness or visual impairment. Tactile symbols allow students to interact, ...
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(2014-05-30)Department: Chemical EngineeringCutaneous defects such as diabetic ulcers, severe burns, and traumatic injuries create a need for cost-effective wound care products that restore tissue function. This dissertation describes the development of an injectable ...
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(2015-04-02)Department: Chemical EngineeringOf the nearly 1.6 million bone graft procedures conducted annually to treat bone fractures in the U.S., ~25% of these fracture patients require rehospitalization due to graft failure. Injectable and settable synthetic bone ...
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(PLoS One, 2019-07-10)Innate CD8 alpha alpha(+) cells, also referred to as iCD8 alpha cells, are TCR-negative intraepithelial lymphocytes (IEL) possessing cytokine and chemokine profiles and functions related to innate immune cells. iCD8 alpha ...
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(2019-06-21)Department: Microbiology and ImmunologyStaphylococcus aureus is able to infect virtually all organ systems and is a frequently isolated etiologic agent of osteomyelitis, a common and debilitating invasive infection of bone. Treatment of osteomyelitis is often ...
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(Vanderbilt University. Peabody College, 2020-05)The Innovation Center of St. Vrain Valley Schools provides STEM-based educational experiences to students in a 50,000 square foot, state-of-the-art facility in Longmont, Colorado. Several local business and industry partners ...
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(2022-05-16)Department: Chemical Engineering--
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(Vanderbilt University. Peabody College, 2021-05)As market-driven businesses, independent schools often rely on innovative practices to stay current for prospective families. In partnership with the National Organization of Independent Schools (NAIS), this mixed-methods ...
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(2018-12-20)Department: NeuroscienceAlzheimer’s disease (AD) is a neurodegenerative disorder characterized by memory loss, language deficits, and executive dysfunction. Currently, there are no disease-modifying therapeutics available and major clinical trials ...
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(Vanderbilt Medical Center, 2010-04-13)Cory Calendine, M.D. is an Assistant Professor of Clinical Orthopaedic Surgery at Vanderbilt University Medical Center. Learn what can be done to minimize discomfort and optimize function in early stage arthritis, as well ...
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(2017-08-04)Department: Nursing ScienceMental health problems are a significant problem among early adolescents and are highly costly to society. Innovative work behaviors (IWB) of middle school faculty and staff are a potentially underused opportunity to address ...
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(2008-04-15)Department: Cell and Development BiologyExport of mature, translationally competent messenger ribonucleoprotein particles (mRNPs) from the nucleus to the cytoplasm is a highly orchestrated process that includes transcription, capping, splicing, and 3' end ...
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(Vanderbilt University. Peabody College, 2008-05-19)Inquiry-oriented instruction is an instructional model that can be implemented in almost any classroom. The following will discuss learners and learning, learners and the environment, curriculum and instructional strategies, ...