Browsing by Subject "Capsid"

Now showing items 1-2 of 2

    • Identification of Novel Determinants of HIV-1 Uncoating in the Capsid Protein 
      Yang, Ruifeng (2009-02-10)
      Department: Microbiology and Immunology
      Uncoating of the viral core following penetration into the target cell represents a fundamentally obscure step in the HIV-1 life cycle. Our laboratory has previously reported that mutations in the CA protein that positively ...
    • The Role Of Intersubunit Interfaces In HIV-1 Capsid Assembly And Stability 
      Yufenyuy, Ernest Limnyuy (2013-04-23)
      Department: Microbiology and Immunology
      This dissertation discusses the role of intersubunit interfaces in HIV-1 capsid assembly and stability. In this study I showed the presence of both the NTD-CTD and CTD-CTD trimer interfaces in mature HIV-1 virions using ...