Browsing by Subject "EPR"
Now showing items 1-7 of 7
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(2011-12-08)Department: Molecular Physiology and BiophysicsPresently we do not completely understand how memories are able to store, retain, and recall information and experiences. The investigation is just beginning and proteins key for the biochemical processes associated with ...
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(2011-09-06)Department: BiochemistryBotulinum neurotoxin (BoNT) belongs to a large class of toxic proteins that act by enzymatically modifying cytosolic substrates within eukaryotic cells. The process by which a catalytic moiety is transferred across a ...
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(2015-03-25)Department: Chemical and Physical BiologyMembrane proteins remain a particular challenge in structural biology. Only approximately 1.5% of reported tertiary structures and around 100 unique polytopic membrane proteins are represented in the Protein Data Bank ...
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(2012-07-26)Department: ChemistryComputational methods that allow application of electron paramagnetic resonance (EPR) spectroscopy data for protein structure prediction were developed. An implicit cone-model for the spin label enabled EPR distance ...
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(2013-12-13)Department: Chemical and Physical BiologyThis thesis has been focused on understanding structure-function relationships of transport proteins and the development of hybrid computational and spectroscopic approaches to understanding protein biology. The widespread ...
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(2016-07-22)Department: ChemistryThe CaMKII enzyme is involved in diverse biological processes including control of heart rate and synaptic plasticity. CaMKII is activated by binding of calmodulin (CaM) and ATP. Its intricate structure and dynamics are ...
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(2010-06-29)Department: Molecular Physiology and BiophysicsThe multidrug transporter EmrE is a proton coupled secondary transporter from Escherichia coli. EmrE confers resistance to a variety of positively charged hydrophobic cations by removing them out of the cell in exchange ...