Browsing by Subject "Epigenetics"

Now showing items 1-3 of 3

    • Consequences of WDR5 Targeted Degradation in Human Cancer Cells 
      Siladi, Andrew; 0000-0001-9548-1860 (2024-03-08)
      Department: Cell & Developmental Biology
      WDR5 is a highly-conserved nuclear protein which facilitates the assembly of histone-modifying complexes involved in a variety of chromatin-based, gene regulatory processes. WDR5 is best known for its role in scaffolding ...
    • Salivary epigenetic biomarkers as predictors of emerging childhood obesity 
      Rushing, Amanda; Sommer, Evan C.; Zhao, Shilin; Po'e, Eli K.; Barkin, Shari L. (BMC Medical Genetics, 2020-02-14)
      Background Epigenetics could facilitate greater understanding of disparities in the emergence of childhood obesity. While blood is a common tissue used in human epigenetic studies, saliva is a promising tissue. Our prior ...
    • Understanding how DNA methylation patterns at enhancers record cellular histories 
      Scott, Timothy Jee Suk; 0000-0002-9454-5700 (2023-11-17)
      Department: Human Genetics
      DNA methylation is an epigenetic modification that is essential for proper multi-lineage cellular differentiation, though the connection between patterned regions of hypomethylation and phenotype is poorly understood. Over ...