Browsing by Subject "FAK"
Now showing items 1-3 of 3
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Focal Adhesion Kinase Mediates Gastrin-Releasing Peptide Receptor-Induced Neuroblastoma Progression (2013-04-18)Department: Cancer BiologyNeuroblastomas express increased levels of gastrin-releasing peptide receptor (GRPR). However, the exact molecular mechanisms involved in GRPR-mediated cell signaling in neuroblastoma growth and metastasis are unknown. In ...
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(2022-07-13)Department: Cancer BiologyIntegrins, the principal extracellular matrix (ECM) receptors of the cell, promote cell adhesion, migration, and proliferation, which are key events for cancer growth and metastasis. To date, most integrin-targeted cancer ...
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(2010-07-14)Department: Cell and Developmental BiologyFocal adhesions (FAs) are sites at the interface between the cell and the ECM, linking integrin receptors and the actin cytoskeleton. In addition to serving as a structural platform, these sites are also robust sites of ...