Browsing by Subject "MRI"
Now showing items 1-20 of 41
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(2012-12-07)Department: Biomedical EngineeringDynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is a method that can be used to quantitatively and qualitatively assess physiological characteristics of tissue. Quantitative DCE-MRI requires an estimate of ...
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(2020-11-16)Department: Biomedical EngineeringThe spinal cord is a narrow, cylindrical structure responsible for rapidly transmitting electrical signals throughout the nervous system and is the primary sensorimotor pathway for the human body. Therefore, damage to the ...
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(2016-06-01)Department: Biomedical EngineeringThe current standard for diagnosing fracture risk comprises measurements of bone mineral density (BMD), primarily by dual-energy X-ray absorptiometry (DXA). However, bone strength is affected by many factors other than ...
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(2022-05-03)Department: Chemical & Physical BiologyPatients who have undergone radiation therapy for brain metastases often have latent lesions such as recurrent tumor or radiation necrosis. Differentiating these lesions in vivo is critical for providing adequate care, but ...
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(2009-04-20)Department: Biomedical EngineeringMagnetic resonance imaging (MRI) is unique in its sensitivity to a wide array of contrast mechanisms in soft tissue. Unfortunately, the physiological and/or microanatomical characteristics that give rise to this contrast ...
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(2008-02-22)Department: Computer ScienceAmong all magnetic resonance imaging sequences, gradient-echo (GE) echo-planar imaging (EPI) has become the most common technique for the study of dynamic brain function and for other high-speed applications like cardiac ...
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Development and Characterization of NMR and MRI Methods for Assessment of Tumor Oxygen Consumption (2012-10-08)Department: PhysicsA common feature of invasive cancers is that they have an upregulation of glucose metabolism and reduced oxygen utilization. The overall goal of this research was to develop a 17Oxygen MRI method to access this aberrant ...
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(2016-11-17)Department: Biomedical EngineeringAdvanced neuroimaging techniques provide the possibility to non-invasively understand and monitor white matter during development and disease. While data from quantitative MRI techniques, such as multiexponential T2 (MET2) ...
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(2017-08-24)Department: Biomedical EngineeringMultiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that is marked by inflammation, demyelination, gliosis and axonal loss. The damage to the CNS from these mechanisms can result in an ...
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(2010-12-06)Department: Biomedical EngineeringIncreased main field (B0) strength in MRI leads to increased signal levels but also causes higher field inhomogeneity (delta-B0). This thesis presents the implementation and evaluation of ‘Dynamic Shimming’, an advanced ...
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(2017-02-09)Department: Biomedical EngineeringDiffusion-weighted MRI (DWI) techniques have demonstrated the ability to non-invasively assess normal and pathological neural tissue. Recently-developed advanced DWI methods have the potential to provide quantitative ...
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Explainable AI in Medical Imaging: Interpreting Multi-Modality Inference with Neuroimaging and EHR (2022-11-07)Department: Electrical EngineeringMedical image processing is the art and science of extracting clinically meaningful information from medical images. One exciting facet of this field is multi-modal modeling: combining various sources of medical data into ...
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(2019-03-22)Department: Electrical EngineeringNeuroimaging provides an opportunity to gain valuable insight onto the microstructural changes in the brain associated with healthy growth and neurological disorders when conducting longitudinal or cross sectional studies. ...
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(2017-02-03)Department: PhysicsClinical imaging and biopsies are major tools for cancer diagnosis. We explore whether serial imaging coupled with a mathematical model could test and refine patient specific forecasts for therapy outcomes. We first ...
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(2011-08-08)Department: Biomedical EngineeringAchieving micron resolutions in magnetic resonance imaging is constrained first by limitations in available signal strength as voxel sizes decrease, and second, by acceptable acquisition times due to the large data sets ...
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(2014-02-20)Department: Human GeneticsAlzheimer’s Disease is an irreversible, degenerative disease of the brain that accounts for a majority of dementia cases each year, in both the general population and in patients with Down Syndrome. The advancement of in ...
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(2013-04-01)Department: Biomedical EngineeringReading is a complex cognitive behavior, which relies on the incorporation of a network of brain regions. White matter is the information transfer pathway between distant brain regions, and thus plays an important role in ...
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(2011-12-22)Department: Computer ScienceClinical research with medical imaging typically involves large-scale data analysis with interdependent software toolsets tied together in a processing workflow. Grid queuing software has become more advanced to meet the ...
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(2017-09-25)Department: Chemical and Physical BiologyCerebrovascular disease (CVD) encompasses conditions that affect the blood supply to the brain. CVD results in hemodynamic impairment, and when the brain can no longer compensate for decreased oxygen delivery to tissue, ...
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(2012-04-11)Department: Biomedical EngineeringMagnetic resonance imaging (MRI) provides methods for characterizing tissue micro-structure using relaxation-based measurements with and without the use of contrast agents (CA). Two techniques, dynamic contrast enhanced ...