Browsing by Subject "Microfluidics"
Now showing items 1-15 of 15
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(2012-01-20)Department: Mechanical EngineeringThe use of electric fields to control colloids has proven to be a promising form of actuation for microfluidic devices. However, limiting our ability to exert precise control over colloidal samples using this technique is ...
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(2015-08-14)Department: Biomedical EngineeringBIOMEDICAL ENGINEERING CHARACTERIZATION OF A PASSIVE DIFFUSION DEVICE FOR ASSAYS OF CHEMOTAXIS AND MORPHOGENESIS IPSHITA CHAKRABORTY Thesis under the direction of Professor John Wikswo Cell migration plays an important ...
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(2005-12-05)Department: Mechanical EngineeringA CELL-BASED MICROPHYSIOMETER SEBASTIAN J. ELUVATHINGAL Thesis under the direction of Professor Mark A. Stremler A computational model of the cell-based microphysiometer is presented in this thesis. The microphysiometer ...
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(2007-08-02)Department: Biomedical EngineeringT cells occupy a central role in cell-mediated immunity and as such, deciphering the signaling events that govern T cell activity is critical in fully understanding the adaptive immune response. Current immunologic ...
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(2008-12-30)Department: Mechanical EngineeringThis thesis evaluates the fundamental understanding of electroosmotic flow in a heterogeneous converging-diverging circular microchannel. Three converging-diverging circular microchannels were modeled and the Poisson-Boltzmann ...
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(2011-01-10)Department: ChemistryThe continual spread of diseases, such as tuberculosis and influenza, which primarily affect poverty-stricken areas, could be slowed if suitable diagnostic resources were to become available. This dissertation examines the ...
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(Vanderbilt University. Dept. of Physics and Astronomy, 2010-04)Enclosed microfluidic devices provide excellent systems for the study of biological processes such as cell-cell, paracrine, and autocrine signaling systems. By minimizing the fluid volume within the chambers, ...
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(Vanderbilt University. Dept. of Physics and Astronomy, 2009-04-20)Precise control of fluid delivery in analytical devices may be achieved by harnessing electroosmotic flow (EOF) in oxidized poly(dimethylsiloxane) microfluidic channels fabricated via soft lithography. However, the ...
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(2009-07-29)Department: Mechanical EngineeringAC-dielelectrophoresis is utilized inside a lab-on-a-chip device to separate particles and cells. Dielectrophoresis is the movement of particles in a non-uniform electric field due to the interaction of the particle's ...
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(Vanderbilt UniversityVanderbilt University, 2007-02-12)Our work is motivated by the desire to quantitatively measure biological dynamical systems. Our agenda is to describe and understand emergent behavior and to explain the observed super robustness of biological dynamics. ...
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(2008-12-06)Department: Mechanical EngineeringThis dissertation presents the study of non-linear induced-charge electrokinetic phenomena and the corresponding applications. The study shows that a nonlinear induced surface charge distribution is immediately caused when ...
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(2008-07-21)Department: PhysicsTraditional particle sensing schemes are based on the resistive-pulse sensing technique. A non-conducting particle displaces a volume of electrolyte, equal to its own volume, from a sensing channel when it flows through. ...
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(2017-06-16)Department: Mechanical EngineeringHow cells detect and respond to mechanical, chemical, and electrical stimuli and make vital cellular decisions accordingly has been extremely puzzling and intriguing. Despite unremitting efforts of generations of researchers, ...
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(2021-09-13)Department: Biomedical EngineeringAs of 2017, improvised explosive devices have accounted for almost 75% of all traumatic injuries to United States soldiers in recent conflicts, yet current biomonitoring efforts through the Embedded Fragments Registry fall ...
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(2022-03-28)Department: Chemical EngineeringHere, we detail the design and fabrication of a two-layer microfluidic device to be used to investigate microtubule dynamics and mechanics in vitro. The design basis was precipitated by our desire to utilize the intrinsic ...