Browsing by Subject "Sepsis"

Now showing items 1-4 of 4

    • Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation 
      Hippensteel, Joseph A.; Uchimido, Ryo; Tyler, Patrick D.; Burke, Ryan C.; Han, Xiaorui; Zhang, Fuming; McMurtry, Sarah A.; Colbert, James F.; Lindsell, Christopher J.; Angus, Derek C.; Kellum, John A.; Yealy, Donald M.; Linhardt, Robert J.; Shapiro, Nathan I.; Schmidt, Eric P. (Critical Care, 2019-07-23)
      BackgroundIntravenous fluids, an essential component of sepsis resuscitation, may paradoxically worsen outcomes by exacerbating endothelial injury. Preclinical models suggest that fluid resuscitation degrades the endothelial ...
    • Scalable Pathogen Extraction Platform for the Treatment of Blood-borne Infections 
      Miller, Sinead Emily (2017-03-31)
      Department: Biomedical Engineering
      Sepsis is a life threatening syndrome caused by infection, affecting over 1 million Americans per year and accounting for over 250,000 deaths annually. Treatment of sepsis relies on appropriate antibiotic therapy targeted ...
    • Sepsis - Part 1 
      Guy, Jeffrey S. (Vanderbilt University. Medical Center, 2007-12-10)
      Sepsis is a common cause of death in the intensive care unit. In this episode I present some of the statistics on septic deaths, introduce the definitions, and present the basic science. Part 2 will cover fluid and drug ...
    • The impact of interleukin-6 on the metabolic response to endotoxin in vivo 
      Tweedell, Andrea Donielle (2005-07-29)
      Department: Molecular Physiology and Biophysics
      Inflammation and insulin resistance are characteristics of endotoxemia. While the role of interleukin-6 (IL-6) in insulin resistant states has been characterized, little is known of its role in the metabolic response to ...