Browsing by Subject "bacterial toxins"
Now showing items 1-2 of 2
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(2011-09-13)Department: Microbiology and ImmunologyThe pathogenesis of Clostridium difficile is dependent on two large homologous toxins, TcdA and TcdB. These toxins contain glucosyltransferase domains that inactivate host Rho proteins by glucosylation. Delivery of the ...
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(2014-07-03)Department: Microbiology and ImmunologyMy project has focused on understanding the structural organization of the clostridial neurotoxins, botulinum and tetanus, that are the causative agents of the neuroparalytic diseases botulism and tetanus. Once the toxins ...