Browsing by Subject "cellular metabolism"
Now showing items 1-4 of 4
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(2016-11-30)Department: Biomedical EngineeringNew therapies are needed to improve the mortality and morbidity of respiratory diseases, but few drug candidates for respiratory diseases are developed and only 3% drug candidates reach market (compared to 6-14% for other ...
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(2017-04-11)Department: Cancer BiologyMelanoma is the deadliest form of skin cancer, and virtually all patients progress on targeted therapies. Dysregulated metabolism has been shown to affect therapy response, so BRAF-mutated melanoma cell line models were ...
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(2015-03-11)Department: Biomedical EngineeringA clinical need exists for improved methods to identify cancer patients with tumors prone to drug resistance, and prescribe effective alternative therapies. Cellular metabolism is a powerful marker of tumor response to ...
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(2012-04-09)Department: Biomedical EngineeringThe optical redox ratio (fluorescence intensity of NADH divided by that of FAD), was acquired for a panel of breast cancer cell lines to investigate how overexpression of human epidermal growth factor receptor 2 (HER2) ...