Browsing by Subject "endothelial cell"
Now showing items 1-3 of 3
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(2007-04-18)Department: Biomedical EngineeringThe failure of synthetic vascular grafts due to de-endothelialization of the lumen as a result of exposure to fluid-induced shear stress prevents the widespread use of such grafts as small-diameter vessel replacements. ...
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(2015-07-16)Department: Molecular Physiology and BiophysicsReduced pancreatic β cell mass is a hallmark of diabetes, which makes the ability to increase or restore β cell mass a major therapeutic goal. While testing the hypothesis that increased endothelial cell signaling would ...
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(2022-11-17)Department: Cell & Developmental BiologyThe overarching goal of my thesis work is to better understand the transcriptional regulation and functions of Sox17 during early development. To start unveiling the complex molecular mechanisms that modulate Sox17 expression, ...