Browsing by Subject "epithelia"

Now showing items 1-4 of 4

    • A Protease-initiated Model of Wound Detection 
      O'Connor, James Thomas; 0000-0003-2642-1594 (2022-02-16)
      Department: Cell & Developmental Biology
      When an organism is injured, the damaged tissue recognizes the presence and severity of the wound and rapidly responds to repair the injury and restore proper tissue functionality. But how do cells first detect the presence ...
    • Characterization of Bves Function in Epithelial Integrity 
      Osler, Megan Emery (2005-11-01)
      Department: Cell and Developmental Biology
      The work contained in this document provides the first description and characterization of Bves, a gene product identified by our laboratory, in epithelial cell types. Studies addressed a central hypothesis that Bves plays ...
    • Genome-Wide CRISPR Screen Identifies Noncanonical NF-κB Signaling as a Regulator of Epithelial Homeostasis 
      Fomicheva, Maria; 0000-0002-0281-0467 (2021-01-06)
      Department: Cell & Developmental Biology
      Epithelial cells possess intrinsic mechanisms to maintain an appropriate cell density for normal tissue morphogenesis and homeostasis. Defects in such mechanisms likely contribute to hyperplasia and cancer initiation. To ...
    • TGF-beta signaling in stromal contribution to prostate cancer progression 
      Ao, Mingfang (2006-07-07)
      Department: Cancer Biology
      Contribution of stromal TGF-b to prostate cancer progression Human prostate carcinoma-associated fibroblasts (CAF) induce malignant transformation in an initiated but non-malignant human prostatic epithelial cell line ...