Browsing by Subject "p73"

Now showing items 1-4 of 4

    • Discovery and characterization of the mTOR-p73 signaling axis in human cancer 
      Rosenbluth, Jennifer Margaret (2009-06-08)
      Department: Biochemistry
      p73, a transcription factor that plays essential roles during development and tumor suppression, shares significant sequence identity with p53. However, p53 and p73 are regulated by different pathways, and p73 is not ...
    • The Essential Role of p73 in Multiciliated Cell Development 
      Marshall, Clayton Benjamin (2016-03-18)
      Department: Biochemistry
      The pivotal role of the transcription factor p53 in tumor suppression remains unchallenged; however, the role of its family member, p73, in normal cellular function and tumorigenesis is far from certain. The goal of this ...
    • The Role of p73 in Basal Keratinocyte Function 
      Beeler, John Scott Austin (2019-11-01)
      Department: Biochemistry
      p63 is a transcriptional regulator of ectodermal development that is required for basal cell proliferation and stem cell maintenance. p73 is a closely related p53 family member that is expressed in select p63-positive basal ...
    • The Role of p73 in Murine Ovarian Follicle Development and Function 
      Santos Guasch, Gabriela Lynette (2018-10-30)
      Department: Biochemistry
      The p53 family of transcription factors, p53, p63 and p73, regulate a wide array of cellular processes from cell cycle control to organ development and cell differentiation. The goal of this dissertation is to understand ...