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Effect of striatal and extrastriatal D2-receptor BP on memory and symptoms of schizotypal personality disorder

dc.contributor.authorPatterson, Katherine A.
dc.date.accessioned2008-07-28T21:34:52Z
dc.date.available2008-07-28T21:34:52Z
dc.date.issued2007-04
dc.identifier.urihttp://hdl.handle.net/1803/1111
dc.descriptionThesis completed in partial fulfillment of the requirements of the Honors Program in the Psychological Sciences Under the direction of David H. Zalden
dc.description.abstractThe integrity of particular dopaminergic projections via the striato-thalamiccortical feedback loop potentially influences specialized aspects of cognition and psychopathology. Research has identified a role for striatal D2 receptors in the cognitive impairments and psychopathological symptoms associated with disorders of the schizophrenia spectrum. Recent developments in PET neuroimaging methods currently permit visualization of D2/D3 receptors in extrastriatal regions. This study evaluated potential correlations between the regional D2/D3 receptor BP in striatal and extrastriatal areas and psychopathological symptoms and memory performance. Significant correlations were observed between particular regions of D2/D3 receptor BP and both verbal and visual memory sub-scales of the Wechsler Memory Scale-III.en
dc.language.isoen_USen
dc.publisherVanderbilt University
dc.subjectD2-Receptor BPen
dc.subjectMemoryen
dc.subject.lcshSchizotypal personality disorderen
dc.subject.lcshMemory -- Physiological aspectsen
dc.subject.lcshDopamine -- Receptorsen
dc.titleEffect of striatal and extrastriatal D2-receptor BP on memory and symptoms of schizotypal personality disorderen
dc.typeThesisen


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