| dc.contributor.author |
Patterson, Katherine A. |
|
| dc.date.accessioned |
2008-07-28T21:34:52Z |
|
| dc.date.available |
2008-07-28T21:34:52Z |
|
| dc.date.issued |
2007-04 |
|
| dc.identifier.uri |
http://hdl.handle.net/1803/1111 |
|
| dc.description |
Thesis completed in partial fulfillment of the requirements of the Honors Program in the
Psychological Sciences
Under the direction of David H. Zald |
en |
| dc.description.abstract |
The integrity of particular dopaminergic projections via the striato-thalamiccortical
feedback loop potentially influences specialized aspects of cognition and
psychopathology. Research has identified a role for striatal D2 receptors in the cognitive
impairments and psychopathological symptoms associated with disorders of the
schizophrenia spectrum. Recent developments in PET neuroimaging methods currently
permit visualization of D2/D3 receptors in extrastriatal regions. This study evaluated
potential correlations between the regional D2/D3 receptor BP in striatal and extrastriatal
areas and psychopathological symptoms and memory performance. Significant
correlations were observed between particular regions of D2/D3 receptor BP and both
verbal and visual memory sub-scales of the Wechsler Memory Scale-III. |
en |
| dc.language.iso |
en_US |
en |
| dc.publisher |
Vanderbilt University |
|
| dc.subject |
D2-Receptor BP |
en |
| dc.subject |
Memory |
en |
| dc.subject.lcsh |
Schizotypal personality disorder |
en |
| dc.subject.lcsh |
Memory -- Physiological aspects |
en |
| dc.subject.lcsh |
Dopamine -- Receptors |
en |
| dc.title |
Effect of striatal and extrastriatal D2-receptor BP on memory and symptoms of schizotypal personality disorder |
en |
| dc.type |
Thesis |
en |
