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Effect of striatal and extrastriatal D2-receptor BP on memory and symptoms of schizotypal personality disorder

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dc.contributor.author Patterson, Katherine A.
dc.date.accessioned 2008-07-28T21:34:52Z
dc.date.available 2008-07-28T21:34:52Z
dc.date.issued 2007-04
dc.identifier.uri http://hdl.handle.net/1803/1111
dc.description Thesis completed in partial fulfillment of the requirements of the Honors Program in the Psychological Sciences Under the direction of David H. Zald en
dc.description.abstract The integrity of particular dopaminergic projections via the striato-thalamiccortical feedback loop potentially influences specialized aspects of cognition and psychopathology. Research has identified a role for striatal D2 receptors in the cognitive impairments and psychopathological symptoms associated with disorders of the schizophrenia spectrum. Recent developments in PET neuroimaging methods currently permit visualization of D2/D3 receptors in extrastriatal regions. This study evaluated potential correlations between the regional D2/D3 receptor BP in striatal and extrastriatal areas and psychopathological symptoms and memory performance. Significant correlations were observed between particular regions of D2/D3 receptor BP and both verbal and visual memory sub-scales of the Wechsler Memory Scale-III. en
dc.language.iso en_US en
dc.publisher Vanderbilt University
dc.subject D2-Receptor BP en
dc.subject Memory en
dc.subject.lcsh Schizotypal personality disorder en
dc.subject.lcsh Memory -- Physiological aspects en
dc.subject.lcsh Dopamine -- Receptors en
dc.title Effect of striatal and extrastriatal D2-receptor BP on memory and symptoms of schizotypal personality disorder en
dc.type Thesis en


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