| dc.contributor.author | Patterson, Katherine A. | |
| dc.date.accessioned | 2008-07-28T21:34:52Z | |
| dc.date.available | 2008-07-28T21:34:52Z | |
| dc.date.issued | 2007-04 | |
| dc.identifier.uri | http://hdl.handle.net/1803/1111 | |
| dc.description | Thesis completed in partial fulfillment of the requirements of the Honors Program in the
Psychological Sciences
Under the direction of David H. Zald | en |
| dc.description.abstract | The integrity of particular dopaminergic projections via the striato-thalamiccortical
feedback loop potentially influences specialized aspects of cognition and
psychopathology. Research has identified a role for striatal D2 receptors in the cognitive
impairments and psychopathological symptoms associated with disorders of the
schizophrenia spectrum. Recent developments in PET neuroimaging methods currently
permit visualization of D2/D3 receptors in extrastriatal regions. This study evaluated
potential correlations between the regional D2/D3 receptor BP in striatal and extrastriatal
areas and psychopathological symptoms and memory performance. Significant
correlations were observed between particular regions of D2/D3 receptor BP and both
verbal and visual memory sub-scales of the Wechsler Memory Scale-III. | en |
| dc.language.iso | en_US | en |
| dc.publisher | Vanderbilt University | |
| dc.subject | D2-Receptor BP | en |
| dc.subject | Memory | en |
| dc.subject.lcsh | Schizotypal personality disorder | en |
| dc.subject.lcsh | Memory -- Physiological aspects | en |
| dc.subject.lcsh | Dopamine -- Receptors | en |
| dc.title | Effect of striatal and extrastriatal D2-receptor BP on memory and symptoms of schizotypal personality disorder | en |
| dc.type | Thesis | en |
