dc.contributor.author | Pines, Julia | |
dc.date.accessioned | 2022-04-14T21:41:11Z | |
dc.date.available | 2022-04-14T21:41:11Z | |
dc.date.issued | 2022-03 | |
dc.identifier.uri | http://hdl.handle.net/1803/17097 | |
dc.description | This paper was written in PSY 4999 Honors Thesis class as part of Dr. Antonia Kaczkurkin's Brains Lab. | en_US |
dc.description.abstract | Anxiety and depressive symptoms can be dissociated into anxious-misery and fear components;
however, little is known about how these two symptom dimensions differ in terms of brain
network properties. Thus, the purpose of this study was to compare the local efficiency of the
default mode network (DMN) and frontoparietal network (FPN) in anxious-misery and fear
symptom dimensions, with examination of six additional networks and small-worldness as
exploratory analyses. To do this, we used data from children ages 9-10 years old from the
Adolescent Brain Cognitive Development (ABCD) Study database. Our primary measure of
interest was local efficiency, which measures the efficiency of information exchange between
nodes of a network when one node is removed. We hypothesized that the DMN would exhibit
increased local efficiency and the FPN would show decreased local efficiency in anxious-misery
symptoms, and both networks would have lower local efficiency in fear symptoms. We found no
significant associations between local efficiency and anxious-misery and fear dimensions or
between small-world omega and the dimensions. However, we found a significant positive
association between anxious-misery symptoms and local efficiency in the FPN and a significant
negative association between fear symptoms and local efficiency in the FPN at uncorrected
levels. These results suggest the need for further study of local efficiency in the FPN in an older
population and the use of other network metrics in anxious-misery and fear symptom
dimensions. | en_US |
dc.description.sponsorship | Thesis completed in partial fulfillment of the requirements of the Honors Program in Psychological Sciences | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Vanderbilt University | en_US |
dc.subject | Brain network | en_US |
dc.subject | Local efficiency | en_US |
dc.subject | Anxiety | en_US |
dc.subject | Depression | en_US |
dc.subject.lcsh | Neurosciences | |
dc.title | Investigating Brain Networks in Anxious-Misery and Fear Symptom Dimensions | en_US |
dc.type | Thesis | en_US |