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Effects of Treatment on Neurocognitive and Psychosocial Development in Adolescent Brain Tumor Survivors

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Effects of Treatment on Neurocognitive and Psychosocial Development in Adolescent Brain Tumor Survivors

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Title: Effects of Treatment on Neurocognitive and Psychosocial Development in Adolescent Brain Tumor Survivors
Author: Wymer, Kevin M.
Abstract: Research on the cognitive and psychosocial effects of treatment for childhood brain tumors has consistently found deficits in these areas. However, the connections between these deficits, as well as their biological basis, are largely unidentified. This study used cognitive tests, parent questionnaires, and functional neuroimaging to further examine possible deficits in these areas of functioning. Brain tumor survivors had increased levels of neurocognitive and psychosocial problems, as well as decreased brain activation during working memory tasks as compared with healthy controls. Additionally, brain activation and social problems were found to be the best predictors of internalizing problems. These results further clarify the deficits observed in brain tumor survivors and support the hypothesis that brain tumor treatment is associated with inhibited brain activation.
Description: This paper serves as a thesis for partial fulfillment of the requirements of the Honors Program in Psychological Sciences. It was completed as part of the PSY 296B Honors Thesis, with Dr. Megan Saylor.
Subject: Functional Neuroimaging
Brain Tumor
Executive Function
Psychosocial Functioning
LCSH Subject: Adjustment (Psychology)
Cancer in children -- Treatment -- Complications
Brain -- Cancer -- Treatment -- Complications
Cognition disorders in adolescence
URI: http://hdl.handle.net/1803/5058
Date: 2012-03-28

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