dc.contributor.advisor | Zald, David H. | |
dc.contributor.author | Qualls, Lydia | |
dc.date.accessioned | 2013-05-19T18:38:45Z | |
dc.date.available | 2013-05-19T18:38:45Z | |
dc.date.issued | 2013 | |
dc.identifier.uri | http://hdl.handle.net/1803/5271 | |
dc.description.abstract | This study investigated how dopamine agonist medication differentially affects reward learning in Parkinson’s patients with and without Impulse Control Disorders (ICDs). We tested 16 patients (8 female, 5 with ICDs, mean age = 62.1) on and off of their dopamine agonist medication using a dynamic foraging task with probability reversals. We hypothesized that patients with ICDs, but not patients without ICDs, would have worse task performance on medication than off medication. Paired samples t-tests confirmed our hypothesis – that task performance was significantly worse on medication than off for ICD patients [t(4) = 2.86, p = .046], but not for non-ICD patients [t(10) = 1.67, p = .126]. This suggests that ICD patients are more vulnerable to medication effects that cause aberrant reward learning, which could be the basis of their impulse control behaviors. | en_US |
dc.description.sponsorship | Thesis completed in partial fulfillment of the requirements of the Honors Program in Psychological Sciences under the advisement of Dr. David Zald. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Vanderbilt University | en_US |
dc.subject | Parkinson's Disease | en_US |
dc.subject | Impulse Control Disorders | en_US |
dc.subject | Reward Learning | en_US |
dc.subject | Dopamine | en_US |
dc.subject | Crab Task | en_US |
dc.subject.lcsh | Cognitive psychology | en_US |
dc.subject.lcsh | Impulse control disorders | en_US |
dc.subject.lcsh | Parkinson's disease | en_US |
dc.subject.lcsh | Dopamine -- Agonists | en_US |
dc.subject.lcsh | Reward (Psychology) | en_US |
dc.title | Effects of Dopamine on Reward Learning in Parkinson’s Patients with Impulse Control Disorders | en_US |
dc.title.alternative | Dopamine and learning in ICD patients | en_US |
dc.type | Thesis | en_US |
dc.description.college | Arts & Sciences | en_US |
dc.description.school | Vanderbilt University | en_US |
dc.description.department | Psychology | en_US |