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Thermal block of action potentials is primarily due to voltage-dependent potassium currents: a modeling study
(Journal of Neural Engineering, 2019-06)
Objective. Thermal block of action potential conduction using infrared lasers is a new modality for manipulating neural activity. It could be used for analysis of the nervous system and for therapeutic applications. We ...
Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content
(Scientific Reports, 2019-09-19)
Brown adipose tissue undergoes a dynamic, heterogeneous response to cold exposure that can include the simultaneous synthesis, uptake, and oxidation of fatty acids. The purpose of this work was to quantify these changes ...
Effects of Prolonged Head-Down Bed Rest on Cardiac and Vascular Baroreceptor Modulation and Orthostatic Tolerance in Healthy Individuals
(Frontiers in Pyhsiology, 2019-08-23)
Orthostatic intolerance commonly occurs after prolonged bed rest, thus increasing the risk of syncope and falls. Baroreflex-mediated adjustments of heart rate and sympathetic vasomotor activity (muscle sympathetic nerve ...
Engineered models to parse apart the metastatic cascade
(NPJ Precision Oncology, 2019-08-21)
While considerable progress has been made in studying genetic and cellular aspects of metastasis with in vitro cell culture and in vivo animal models, the driving mechanisms of each step of metastasis are still relatively ...
Thermal block of action potentials is primarily due to voltage-dependent potassium currents: a modeling study
(Journal of Neural Engineering, 2019-06)
Objective. Thermal block of action potential conduction using infrared lasers is a new modality for manipulating neural activity. It could be used for analysis of the nervous system and for therapeutic applications. We ...