Search
Now showing items 1-10 of 12
Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes
(HEPATOLOGY COMMUNICATIONS, 2019-07)
The accumulation of excess fat in the liver (hepatic steatosis) in the absence of heavy alcohol consumption causes nonalcoholic fatty liver disease (NAFLD), which has become a global epidemic. Identifying metabolic risk ...
In vivo magnetic resonance imaging of treatment-induced apoptosis
(SCIENTIFIC REPORTS, 2019-07-02)
Imaging apoptosis could provide an early and specific means to monitor tumor responses to treatment. To date, despite numerous attempts to develop molecular imaging approaches, there is still no widely-accepted and reliable ...
Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with Lu-177-Dotatate: an analysis of the NETTER-1 study
(European Journal of Nuclear Medicine and Molecular Imaging, 2020-09)
Purpose To assess the impact of baseline liver tumour burden, alkaline phosphatase (ALP) elevation, and target lesion size on treatment outcomes with Lu-177-Dotatate. Methods In the phase 3 NETTER-1 trial, patients with ...
snapMRF: GPU-accelerated magnetic resonance fingerprinting dictionary generation and matching using extended phase graphs
(Magnetic Resonance Imaging, 2020-02)
Purpose:: Magnetic resonance fingerprinting (MRF) is a state-of-the-art quantitative MRI technique with a computationally demanding reconstruction process, the accuracy of which depends on the accuracy of the signal model ...
Quantitative temporal diffusion spectroscopy as an early imaging biomarker of radiation therapeutic response in gliomas: A preclinical proof of concept
(Advances in Radiation Oncology, 2019-04)
Purpose: This study aims to test the ability of quantitative temporal diffusion spectroscopy (qTDS) to assess cellular changes associated with radiation-induced cell death in a rat glioma model.
Methods and Materials: ...
3D printable Point Source Holder for PET and SPECT
(AAPM, 2022-07)
Task Group Report 126 was created to summarize acceptance testing and quality assurance tests for PET/CT systems. There are very few specialized phantoms in this report but one is a phantom that places points sources in ...
Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases:Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933
(Advances in Radiation Oncology, 2019-10-10)
Purpose: NRG Oncology's RTOG 0933 demonstrated benefits to memory preservation after hippocampal avoidant whole-brain radiation therapy (HA-WBRT), the avoidance of radiation dose to the hippocampus (using intensity modulated ...
3D printable Nuclear Medicine SPECT Cardiac Phantom
(Medical Physics, 2022)
Purpose:
The purpose of this study was to validate a 3D-printed nuclear cardiac phantom to create a low cost, user-friendly phantom for perfusion imaging that is easily implemented with modern cardiac SPECT systems. This ...
P-31 magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations
(NMR in Biomedicine, 2020-02)
Skeletal muscle phosphorus-31 P-31 MRS is the oldest MRS methodology to be applied to in vivo metabolic research. The technical requirements of P-31 MRS in skeletal muscle depend on the research question, and to assess ...
Surgical outcomes of adnexal masses classified by IOTA ultrasound simple rules
(Scientific Reports, 2022-12-17)
IOTA (International Ovarian Tumor Analysis) Simple Rules classifies adnexal masses as benign, malignant, or indeterminate based on sonographic features. We seek to determine if IOTA inappropriately directed women to surgery, ...