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Automated cell boundary and 3D nuclear segmentation of cells in suspension
(Scientific Reports, 2019-07-15)
To characterize cell types, cellular functions and intracellular processes, an understanding of the differences between individual cells is required. Although microscopy approaches have made tremendous progress in imaging ...
Inhibition of MYC by the SMARCB1 tumor suppressor
(Nature Communications, 2019-05-01)
SMARCB1 encodes the SNF5 subunit of the SWI/SNF chromatin remodeler. SNF5 also interacts with the oncoprotein transcription factor MYC and is proposed to stimulate MYC activity. The concept that SNF5 is a coactivator for ...