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Targeting WDR5: A WINning Anti-Cancer Strategy?
(EPIGENETICS INSIGHTS, 2019-07-18)
WDR5 is a component of multiple epigenetic regulatory complexes, including the mixed lineage leukemia (MLL)/SET complexes that deposit histone H3 lysine 4 methylation. Inhibitors of an arginine-binding cavity in WDR5, known ...