The biophysical and biochemical study of membrane proteins is uniquely challenged by the lipid bilayer environment in which membrane proteins reside. While fantastic methods have been developed over the years, there is ...

The goal of the presented work is to develop robust magnetic resonance imaging (MRI) techniques to improve current and enable future applications of thermal therapies. Focused ultrasound therapy is an emerging treatment ...

Nucleic acids have emerged as leading biomarkers for diagnostic technologies, as they allow for extremely specific discrimination of targets via base-pair binding. Overcoming the obstacles posed enzymes, non-enzymatic ...

Bone fragility is a widespread problem worldwide and the current clinical standard diagnosis method for evaluating bone fragility through Bone Mineral Density (BMD) is not always effective in predicting bone fracture risk. ...

Focused ultrasound (FUS) is a non-invasive therapeutic technology that can use ultrasonic energy to precisely target tissue deep inside the body without incisions or radiation. However, for the safety and credibility of ...

Direct functionalization of unactivated C-H bonds presents a longstanding challenge in the field of synthetic chemistry, largely addressed by the use of low-valent transition metal catalysts and development of corresponding ...

A Literacy Professional Development engaged in a year-long quality improvement project to seek ways to define and deepen its impact on its clients' student learning. Through the lens of self-efficacy and customer loyalty ...

Quantitative structure activity relationship (QSAR) modeling using high-throughput screening (HTS) data enables the development of predictive models for in silico screening. A cheminformatics framework termed BCL::ChemInfo ...

Thyroid cancer incidence is rapidly increasing in the United States, with over 45,000 patients projected to be diagnosed in 2022. While the vast majority of patients respond well to first line treatment, approximately 20% ...

Magnetic resonance microscopy (MRM) is capable of probing fine structures and complex functions of living tissue. MRM suffers from decreased SNR and long scan times approaching 10s of hours to achieve sub 10 µm isotropic ...