Browsing by Title
Now showing items 2295-2314 of 17421
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(2018-04-10)Department: Chemical and Physical BiologyModern single-cell technologies allow multiplexed sampling of cellular states within a tissue. However, computational tools that can infer developmental cell-state transitions reproducibly from such single-cell data are ...
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(2022-05-03)Department: Chemical & Physical BiologyPatients who have undergone radiation therapy for brain metastases often have latent lesions such as recurrent tumor or radiation necrosis. Differentiating these lesions in vivo is critical for providing adequate care, but ...
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(2018-04-23)Department: Chemical and Physical BiologyBioactive natural products are small molecules produced by organisms of all domains to influence and respond to environmental conditions. These molecules have evolved to recognize both intra and inter cellular targets and ...
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(2012-08-31)Department: Cancer BiologyThese studies tested the hypothesis that cell-extracellular matrix (ECM) interactions promote the maturation of invadopodia to fully functional structures. I demonstrate that invadopodia-associated ECM degradation is ...
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(2019-07-19)Department: Chemical EngineeringPolyurethanes (PURs) are an attractive material for tissue engineering bone graft substitutes since they can be formulated to be injectable, settable, and biocompatible, and their mechanical properties and degradation rates ...
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(Communications Biology, 2019-09-02)The kidney's inherent complexity has made identifying cell-specific pathways challenging, particularly when temporally associating them with the dynamic pathophysiology of acute kidney injury (AKI). Here, we combine renal ...
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(2014-12-31)Department: Cancer BiologyNon alcoholic fatty liver disease (NAFLD), is recognized as the one of the most common causes of liver disease in the United States and worldwide. NAFLD is associated with increased risk of development of hepatocellular ...
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(2021-06-15)Department: Cell & Developmental BiologyMulticellular organisms adapt to the environment by sensing it and reacting to it through neuronal networks that are in place to transform a stimulus into a behavioral effect. A functional nervous system requires pruning ...
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(2023-04-10)Department: Cell & Developmental BiologyMicrovilli are actin-based surface protrusions that have been repurposed throughout evolution to fulfill diverse cell functions including mechanosensation in inner ear hair cells and nutrient absorption in transporting ...
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Cellular instability phenomenon in premixed tubular flames and non-premixed opposed tubular flames (2008-09-19)Department: Mechanical EngineeringInstability phenomenon (cellular structure or multi-petal structure) and extinction behavior are studied in premixed tubular flames and non-premixed opposed tubular flames. A newly designed tubular burner that is capable ...
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(2022-09-09)Department: PhysicsEpithelial wound healing is a vital biological process that involves the coordination of cells across a wounded tissue. Cells must be able to integrate both physical and chemical signals resulting from a wound in order to ...
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(2017-04-11)Department: Cancer BiologyMelanoma is the deadliest form of skin cancer, and virtually all patients progress on targeted therapies. Dysregulated metabolism has been shown to affect therapy response, so BRAF-mutated melanoma cell line models were ...
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(2021-08-13)Department: Cancer BiologyMetabolism underpins many processes in cellular biology. Many diseases including cancer often involve aberrant metabolic pathways with altered reliance on metabolites, metabolic enzymes, or metabolic regulators. B lymphocytes ...
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Cellular mRNA Export Factor UAP56 Recognizes Nucleic Acid Binding Site of Influenza Virus NP Protein (2020-05-19)Department: Chemical & Physical BiologyThe nucleoprotein (NP) of the influenza A virus forms the structural packaging factor for the viral genome by its binding to viral RNA as part of the viral ribonucleoprotein. It had been previously shown that replication ...
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(2019-05-15)Department: Cell and Developmental Biology<em>Helicobacter pylori</em> is a Gram-negative bacterium that colonizes the human stomach. More than 50% of the global population is chronically infected with <em>H. pylori</em>, and infection with <em>H. pylori</em> is ...
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(2010-03-29)Department: NeuroscienceRolling Blackout (RBO), a Drosophila EFR3 homolog, is an integral membrane protein predicted to be a lipase. A conditional temperature-sensitive (TS) mutant (rbots) displays paralysis following a 25-37oC temperature shift, ...
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Centennial Professor of Philosophy John Lachs: "Great ideas of the 19th century" Nov. 10, 2010 class (Vanderbilt University, 2010-11-29)
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Centennial Professor of Philosophy John Lachs: "Great ideas of the 19th century" Nov. 3, 2010 class (Vanderbilt University, 2010-11-29)
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Centennial Professor of Philosophy John Lachs: "Great ideas of the 19th century" Oct. 13, 2010 class (Vanderbilt University, 2010-11-29)
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Centennial Professor of Philosophy John Lachs: "Great ideas of the 19th century" Oct. 27, 2010 class (Vanderbilt University, 2010-11-29)