Browsing by Title
Now showing items 2427-2446 of 17382
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(2023-03-27)Department: NeuroscienceEpilepsy is one of the most common neurological disorders, and current treatments fail to provide seizure control for ~30% of patients. Most pharmacological treatments target ion channels and neurotransmission, yet the ...
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(2023-11-07)Department: Computer ScienceMedical imaging techniques, such as multi-modality Magnetic Resonance Imaging (MR) and Computed Tomography (CT), have been invaluable for the early detection, diagnosis, and treatment of diseases. The process of annotating ...
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(2021-04-02)Department: Cell & Developmental BiologyCancer is a heterogeneous disease displaying a variety of cell populations inter- and intra-tumorally. This heterogeneity poses a challenge to cancer treatment, as more heterogeneous cellular populations are more prone to ...
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(2022-11-22)Department: NeuroscienceAutism has long been considered an empathy related condition, yet empirical evidence supporting this claim has been inconclusive. While most cognitive empathy assessments suggest a decreased capacity for emotion recognition, ...
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(2009-12-16)Department: Chemical EngineeringBimodal analysis, a cellular-scale approach to studying eukaryotic single cell migration by performing a model-based analysis of single cell video-microscopy data, is described. The bimodal framework that is a generalization ...
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Characterizing memory space: The neural representational structure of episodic and semantic memory (2022-09-16)Department: PsychologyMemories are not preserved in the past, they help us navigate the present and predict the future. Our representation of the world is constantly evolving as we experience time unfolding continuously, yet our past is made ...
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(2019-08-08)Department: Hearing and Speech SciencesCognitive rehabilitation following brain injury rests on the ability of clinicians to support their patients’ (re)learning of knowledge, skills, and strategies. Learning and memory are therefore central to the success of ...
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CHARACTERIZING OPEN CLUSTERS AND SPECTROSCOPIC ECLIPSING BINARIES WITH MACHINE LEARNING FRAMEWORKS (2023-07-18)Department: AstrophysicsIn recent years there has been an explosion of data from space-based and ground-based astronomical surveys. This has led to the necessity of moving away from single-use, boutique analyses to flexible automated data analysis ...
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(2017-03-22)Department: Hearing and Speech SciencesThe ability to adequately perceive and utilize the prosody of spoken language is important for successful communication. Children with hearing loss who use cochlear implants have demonstrated deficits in perception of ...
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Characterizing Rare Disease-Causing Mutations in Genes Affecting Cation-Coupled Chloride Cotransport (2020-03-27)Department: NeuroscienceSeveral human diseases have been associated with mutations in genes affecting cation-chloride cotransporters. My dissertation characterizes two single clinical cases with mutations in genes encoding protein kinase D1 (PKD1) ...
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Characterizing temporal and spatial trends in soil geochemistry on Polder 32, southwest Bangladesh (2015-07-21)Department: Earth and Environmental SciencesSoil samples were collected during three field campaigns to determine seasonal and spatial trends of soil salinity, soil acidity and arsenic concentrations on Polder 32 in coastal Bangladesh. Many farmers on Polder 32 use ...
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(2021-08-13)Department: Molecular Physiology & BiophysicsFunctional seizures (FS), paroxysmal episodes that present like epileptic seizures but display no aberrant brain electrical patterns, are understudied. Patients have few treatment modalities and a high rate of comorbidities. Our ...
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(2021-03-25)Department: Biomedical EngineeringFunctional differences are exhibited by the dominant and non-dominant lower limbs during overtly asymmetric bilateral tasks (e.g., kicking a soccer ball). However, current biomechanical analyses of human locomotion typically ...
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(2013-07-18)Department: Biological SciencesCells that are migrating in a chemical gradient display a polarized distribution of signaling and cytoskeletal components. We have investigated the mechanism of polarity establishment by using the model system Dictyostelium ...
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(2012-06-11)Department: Biological SciencesTelomeres are protective protein/DNA complexes that cap the ends of linear chromosomes. The repetitive, TG-rich telomeric sequences are elongated by the telomerase ribonucleoprotein. In Saccharomyces cerevisiae, the ...
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(2021-04-12)Department: NeuroscienceArabic digits are perhaps the most ubiquitous symbol set used regardless of one’s native language and script. The ability to read numerals fluently is critical to succeed in the modern world. Yet, we know very little about ...
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(2023-03-24)Department: Biomedical EngineeringDehydration can have profound consequences for high performance populations such as athletes and military personnel, including cardiovascular strain, delirium, and reductions in performance. Current hydration monitoring ...
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(2014-03-25)Department: Environmental EngineeringRecent increases in competition for water, food, and energy are exposing the complex network threading these resources together. My dissertation explores how the interactions among these resources affect decisions about ...
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(2007-12-31)Department: Materials Science and EngineeringA study on the dynamics and nature of the processes leading to the redistribution of energy and charge after photoexcitation of single-wall carbon nanotubes is presented. Ultrafast as well as continuous wave spectroscopies ...
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(2014-07-30)Department: Electrical EngineeringSingle-event effects (SEEs) in microelectronic devices present a serious reliability concern for space-based applications, where electronic components are exposed to highly energetic ionizing radiation. Single-event effects ...