Browsing by Title
Now showing items 3392-3411 of 17421
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(The George Washington Law Review, 2007)In Chevron, U.S.A. v. Natural Resources Defense Council, Inc., the Supreme Court famously held that judicial deference to agency interpretations of ambiguous statutes is appropriate largely because the executive branch is ...
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(2023-08-31)Department: Cell & Developmental BiologyThe ductus arteriosus (DA) is a muscular artery which helps to define the fetal pattern of the circulatory system. After birth, the DA undergoes muscular constriction and remodeling which establish the adult division between ...
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(2023-07-11)Department: Biomedical InformaticsPolygenic scores (PGS) aim to capture a person’s genetic predisposition to a disease or trait. There is substantial interest in applying PGS to clinical settings to identify patients at elevated risk for disease. Given its ...
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(2022-11-18)Department: Microbe-Host InteractionsViruses with multi-segmented genomes are unique in their capacity to readily exchange large amounts of genetic information via a process known as reassortment. Reassortment requires a considerable amount of genetic ...
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(2023-01-20)Department: Cell & Developmental BiologyMicrovilli are actin-bundle-supported surface protrusions that play essential roles in diverse epithelial functions, from nutrient absorption to mechanosensation. Despite the importance of microvilli for proper epithelial ...
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(2014-11-26)Department: Biomedical InformaticsElectronic Health Records (EHRs) allow for the digital capture of patient information and have proven to be a valuable tool for patient treatment. In this dissertation, I explore reuse of EHR data for clinical and genomic ...
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(2018-03-22)Department: Microbiology and ImmunologyCeliac disease is an immune-mediated intestinal disorder that occurs in genetically predisposed individuals exposed to dietary gluten. Viral infections are associated with the induction of celiac disease. However, not all ...
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(2023-05)Texas Tech University (TTU), the largest comprehensive higher education institution in the western two-thirds of the state, opened its doors in 1925 and boasts a rich history of research programs designed to enrich lives ...
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(2017-11-21)Department: Community Research and ActionRecent research has suggested that a social justice education (SJE) increases students’ awareness of social issues affecting communities, while simultaneously equipping students with skills they can apply in a real-world ...
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(2017-11-30)Department: Microbiology and ImmunologyThe goal of this thesis was to investigate the role of the IsdG family of heme oxygenases within microbial cells. In Chapter II, I identified the first IsdG family member in a eukaryotic organism and expanded the IsdG ...
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(2022-01-04)Department: Microbe-Host InteractionsCoronaviruses (CoVs) are a genetically diverse group of positive-sense single-stranded RNA viruses containing the largest known genome of any RNA virus, >30 kb, and responsible for the current COVID-19 pandemic (SARS-CoV-2). ...
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(2015-03-26)Department: Chemical and Physical BiologyClostridium difficile is a common nosocomial infection that encompasses a range of clinical symptoms from mild diarrhea to complicated pseudomembranous and fulminant colitis. C. difficile secretes two large toxins, TcdA ...
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(2023-03-24)Department: Molecular Pathology & ImmunologyInflammation of bone, or osteomyelitis, is most commonly caused by infection with the Gram-positive bacterium Staphylococcus aureus. During S. aureus osteomyelitis, the homeostasis-maintaining activities of bone cells are ...
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(2022-03-15)Department: Microbe-Host InteractionsUropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections and among the most successful human bacterial pathogens worldwide. Despite being a facultative anaerobe, UPEC requires aerobic respiration ...
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(2022-06-10)Department: Microbe-Host InteractionsGroup B Streptococcus (GBS), or Streptococcus agalactiae, is one of the leading causes of infection-related adverse pregnancy and neonatal outcomes, which include stillbirth, chorioamnionitis, preterm birth, and neonatal ...
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(2011-04-05)Department: MathematicsThis work explores some aspects of the deformation/rigidity theory of II_1 factors. The work primarily addresses the deformation side of deformation/rigidity, developing techniques to accommodate natural deformations coming ...
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(Vanderbilt University. Dept. of Physics and Astronomy, 2022-12)Strong coupling of cavity electromagnetic modes and molecules has emerged as an area of intense theoretical and experimental interest. Such systems are of particular interest due to their ability to modify the physical ...
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(Vanderbilt University. Peabody College, 2016-10-12)This paper argues against the sense of inescapable reality engendered by capitalism and discusses how playing out a re-imagined reality at school could defy this world. I utilize the concept of “figured worlds” as a lens ...
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(2021-05-19)Department: MathematicsIn this thesis, we focus on topics related to the Dehn function of a finitely presented metabelian group and relative Dehn function of a finitely generated metabelian groups. We establish a commutative algebra approach to ...
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(2023-11-17)Department: ChemistryThe molecular mechanisms associated with aging and age-related diseases are still being discovered. Spontaneous degradation of proteins can lead to the formation of post-translational modifications (PTMs). Among the PTMs ...