Browsing by Title
Now showing items 3395-3414 of 17382
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(2022-01-04)Department: Microbe-Host InteractionsCoronaviruses (CoVs) are a genetically diverse group of positive-sense single-stranded RNA viruses containing the largest known genome of any RNA virus, >30 kb, and responsible for the current COVID-19 pandemic (SARS-CoV-2). ...
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(2015-03-26)Department: Chemical and Physical BiologyClostridium difficile is a common nosocomial infection that encompasses a range of clinical symptoms from mild diarrhea to complicated pseudomembranous and fulminant colitis. C. difficile secretes two large toxins, TcdA ...
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(2023-03-24)Department: Molecular Pathology & ImmunologyInflammation of bone, or osteomyelitis, is most commonly caused by infection with the Gram-positive bacterium Staphylococcus aureus. During S. aureus osteomyelitis, the homeostasis-maintaining activities of bone cells are ...
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(2022-03-15)Department: Microbe-Host InteractionsUropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections and among the most successful human bacterial pathogens worldwide. Despite being a facultative anaerobe, UPEC requires aerobic respiration ...
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(2022-06-10)Department: Microbe-Host InteractionsGroup B Streptococcus (GBS), or Streptococcus agalactiae, is one of the leading causes of infection-related adverse pregnancy and neonatal outcomes, which include stillbirth, chorioamnionitis, preterm birth, and neonatal ...
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(2011-04-05)Department: MathematicsThis work explores some aspects of the deformation/rigidity theory of II_1 factors. The work primarily addresses the deformation side of deformation/rigidity, developing techniques to accommodate natural deformations coming ...
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(Vanderbilt University. Dept. of Physics and Astronomy, 2022-12)Strong coupling of cavity electromagnetic modes and molecules has emerged as an area of intense theoretical and experimental interest. Such systems are of particular interest due to their ability to modify the physical ...
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(Vanderbilt University. Peabody College, 2016-10-12)This paper argues against the sense of inescapable reality engendered by capitalism and discusses how playing out a re-imagined reality at school could defy this world. I utilize the concept of “figured worlds” as a lens ...
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(2021-05-19)Department: MathematicsIn this thesis, we focus on topics related to the Dehn function of a finitely presented metabelian group and relative Dehn function of a finitely generated metabelian groups. We establish a commutative algebra approach to ...
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(2023-11-17)Department: ChemistryThe molecular mechanisms associated with aging and age-related diseases are still being discovered. Spontaneous degradation of proteins can lead to the formation of post-translational modifications (PTMs). Among the PTMs ...
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(Delaware Journal of Corporation Law, 2018)The 1980’s is appropriately considered the Golden Age of Delaware corporate law. Within that era, the Delaware courts won international attention by not just erecting the legal pillars that frame today’s corporate governance ...
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(Boston College Law Review, 3/28/2014)The Supreme Court’s increasing use of science and social science in its decision-making has a rationalizing effect on law that helps ensure that a rule will have its desired effect. But resting doctrine on the shifting ...
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(Vanderbilt University, 2010-01-25)
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(Molecular Neurobiology, 2019-08)Autism and epilepsy are diseases which have complex genetic inheritance. Genome-wide association and other genetic studies have implicated at least 500+ genes associated with the occurrence of autism spectrum disorders ...
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(BMC Developmental Biology, 2019-07-08)BackgroundThe Tet protein family (Tet1, Tet2, and Tet3) regulate DNA methylation through conversion of 5-methylcytosine to 5-hydroxymethylcytosine which can ultimately result in DNA demethylation and play a critical role ...
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(2012-12-12)Department: EnglishThis dissertation pairs fictional texts with periodicals in four time periods that span the nineteenth century to compare the changing narrative perspectives encoded in the editorial “We,” or as Anthony Trollope called it, ...
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(Cells, 2020-01)Exploring the interactions between the Ca2+ binding protein calmodulin (CaM) and its target proteins remains a challenging task. Members of the Munc13 protein family play an essential role in short-term synaptic plasticity, ...
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(2019-03-22)Department: Microbiology and ImmunologyUrinary tract infections (UTIs) are very common, the disease severity can encompass a broad range of clinical diagnoses, including acute cystitis, pyelonephritis, catheter-associated infection, and asymptomatic bacteriuria. ...
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(2008-03-19)Department: Cancer BiologyGastric adenocarcinoma is the second leading cause of cancer-related death in the world, and infection with Helicobacter pylori is the strongest known risk factor for this malignancy. Adherence of H. pylori to gastric ...
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(2021-05-11)Department: NeuroscienceStress is critical to every organism’s ability to adapt and survive. This dissertation reviews the history of stress research and reviews stress physiology across a variety of organ systems. Neurocircuitry that is involved ...