Browsing by Title
Now showing items 3735-3754 of 17421
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(2018-04-16)Department: ChemistryThe three diseases most commonly linked to poverty—malaria, tuberculosis (TB), and HIV/AIDS—are the cause of 8.7 million deaths globally each year. Early and accurate diagnosis of these infectious disease is critically ...
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(2015-04-08)Department: Chemical EngineeringFor the application of cell therapy in tissue repair, there is a compelling need for the development of suitable cell carriers, which will function as synthetic analogs of the extracelluar matrix (ECM) that provide a ...
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(2014-04-15)Department: Chemical EngineeringOverall cancer fatalities have stabilized since the early 1990s, however the prevalence of cancer is still remarkably high for men (45%) and women (38%). While the recent advances in treatments for cancers have increased ...
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Development of prognostic model for breast cancer in Shanghai Breast Cancer Survival Study (SBCSS) (2015-07-23)Department: BiostatisticsWe developed prognostic models to predict five-year overall survival (OS), ten-year overall survival (OS), and five-year relapse-free survival (RFS) from Shanghai Breast Cancer Survival Study (SBCSS). SBCSS is a large, ...
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(2013-04-16)Department: ChemistryDisorders of the central nervous system (CNS) continue to be among mankind’s most devastating illnesses. Along with causing enormous suffering for those affected, mental disorders place an extreme socioeconomic burden on ...
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(2016-12-06)Department: Biomedical EngineeringInflammatory bowel disease (IBD), comprised of Crohn’s disease and ulcerative colitis, is a complex autoimmune condition characterized by periods of disease flare and remission that seriously impact patient quality of life. ...
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(2015-07-22)Department: ChemistryDelivery of diagnostic tools to low-resource settings under the burden of the malaria epidemic faces numerous challenges. These underdeveloped areas are often characterized by poverty, absent or intermittent electricity, ...
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(2017-04-11)Department: ChemistryIn low-resource areas of the world, accurate diagnosis of disease is especially challenging, as resources are limited and environmental conditions uncontrolled. Consequently, reliable low-resource diagnostics must be simple, ...
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(2013-12-12)Department: Biomedical EngineeringA series of novel, physiologically-responsive poly(ε-caprolactone)-co-(α-allyl carboxylate-ε-caprolactone) [x%PCL-y%ACPCL (x and y: molar ratio)] shape memory polymers (SMPs) were synthesized with excellent shape memory ...
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(2014-03-19)Department: Chemical and Physical BiologySimple and rapid methods for detecting RNA biomarkers from patient samples are especially desirable in settings with limited access to laboratory resources and trained personnel. The focus of this dissertation is on the ...
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(2010-04-12)Department: PhysicsSiliSPECT, a multi-pinhole, multi-detector SPECT system, was designed to image targeted regions of rodents at sub-300 micron resolution with stationary data acquisition. High spatial resolution is achieved with thick silicon ...
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(2011-12-06)Department: Civil EngineeringRoadway closures due to highway incidents are detrimental to the American economy and result in lost time for motorists. Route diversion can help lessen the effects of highway incidents, if the decision is based upon a ...
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(2008-07-11)Department: Mechanical EngineeringThis dissertation presents the development of ultra-sensitive fluidic sensors and molecular dynamics studies of ion and water distribution in highly confined nanochannels. The fluidic sensor is based on resistive pulse ...
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(2014-03-05)Department: Electrical EngineeringRecent development of nanocrystalline diamonds has demonstrated the potential use of diamond material for vacuum microelectronics. Apart from the advantages of conventional microcrystalline diamond, nanodiamond with smaller ...
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(2014-12-03)Department: Chemical and Physical BiologyCurrent chemotherapeutic treatments for cancer utilize systemic administration of cytotoxic drugs and produce many side effects in healthy tissues, making optimal treatment of cancer hard to achieve. Tumor targeted ...
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(2010-08-06)Department: Hearing and Speech SciencesThe brain is continuously processing many sources of sensory information. One of the key strategies it uses to determine what stimuli are associated with one another is the temporal delay between multisensory inputs. ...
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(2010-08-05)Department: Cell and Developmental BiologyMutations in human microcephalin (MCPH1) result in a form of autosomal recessive primary microcephaly, a disorder of fetal brain growth characterized by a severely reduced cerebral cortex and head size with mental retardation. ...
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(Vanderbilt University, Department of History, 2016)Medieval representations of death can illuminate how individuals conceptualised the experience. The poem "A Disputacione Betwyx The Body and Wormes" is a productive lens through which to consider contemporary notions of ...
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(2016-08-24)Department: PhilosophyThis dissertation examines the injustices perpetrated against Indigenous people in Canada within the explicit framework of democratic theory. I examine the ability of Deweyan democracy as a purported problem-solving mechanism ...
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(2014-02-21)Department: Mechanical EngineeringThis dissertation offers ways that the dexterity and guidance associated with image-guided robotic surgery can be delivered without automation. The overall objective is to provide highly capable instruments to surgeons, ...