Browsing by Title
Now showing items 4788-4807 of 17423
-
(2011-04-16)Department: Chemical EngineeringDNA microarrays have become an increasingly important tool for genomic investigations. This work is directed toward establishing methods and surface architectures that allow the monitoring of DNA hybridization and ...
-
(2023-07-14)Department: Biomedical EngineeringIn the United States, cancer deaths have dropped by 27% in the last 20 years. Although there has been great progress, effective treatment options for metastatic colorectal cancer (CRC) are still limited, and stage 4 cancers ...
-
(2023-07-14)Department: Biomedical EngineeringIn the United States, cancer deaths have dropped by 27% in the last 20 years. Although there has been great progress, effective treatment options for metastatic colorectal cancer (CRC) are still limited, and stage 4 cancers ...
-
(NPJ Precision Oncology, 2019-08-21)While considerable progress has been made in studying genetic and cellular aspects of metastasis with in vitro cell culture and in vivo animal models, the driving mechanisms of each step of metastasis are still relatively ...
-
(2022-05-16)Department: Biomedical EngineeringNeurodegenerative diseases are increasing in prevalence as the population of the United States ages. There are currently no cures or effective treatments for many of these diseases, likely in part due to the lack of ...
-
(Vanderbilt University. Dept. of Physics and Astronomy, 2011-04)The study of living specimens is essential to the understanding of organismal behavior. Unfortunately, a major difficulty in the study of live organisms is that many move in and out of the field of view or focal plane ...
-
(2022-03-30)Department: OtherSmall cell lung cancer (SCLC) is a highly aggressive disease, characterized by a signature “tumor recurrence” during treatment, wherein after initial favorable response, tumors re-establish themselves and no longer respond ...
-
(2016-04-15)Department: Biomedical EngineeringTissue engineering promises to solve the ever-increasing organ donor shortage, as well as to provide personalized and customized cures for numerous life-threatening diseases and organ/tissue failures. While significant ...
-
(2018-09-21)Department: Chemical and Physical BiologyAntibodies are a key component of the human immune response to infectious disease. The best anti-viral antibody response is one that is potent and broad, covering a large number of the many diverse viral variants. ...
-
(2018-06-26)Department: Interdisciplinary Materials ScienceRenewable energy from wind and solar are no longer solely motivated by their environmental benefits but are now also economically competitive. Batteries are a key component in both the renewable grid infrastructure and ...
-
(2021-12-01)Department: Chemical EngineeringThe development of cancer occurs when immunosuppression inhibits the naturally occurring process through which the immune system recognizes and eliminates cancer cells (i.e. the cancer-immunity-cycle). While clinically ...
-
(2016-12-21)Department: PhysicsEngineering light-matter interaction at the nanoscale has the promise to enable technological advances in a wide range of technological applications, including biomolecular sensing, communication, quantum optics, displays, ...
-
(2023-03-13)Department: Biomedical EngineeringImmune checkpoint blockade (ICB) has revolutionized cancer treatment and has led to complete and durable responses, but only for a minority of patients. Resistance to ICB can largely be attributed to insufficient number ...
-
(2020-06-12)Department: Biomedical EngineeringTissue-resident memory T cells (TRM) patrol non-lymphoid organs and provide superior protection against pathogens that commonly infect mucosal and barrier tissues, such as the lungs, intestine, liver, and skin. At these ...
-
(2022-03-25)Department: Biomedical EngineeringTraditional approaches to cancer vaccines elicit weak CD8+ T cell responses and have largely failed to meet clinical expectations. This is in part due to inefficient antigen cross-presentation, inappropriate selection of ...
-
(2008-02-22)Department: Chemical EngineeringIn this dissertation we describe a strategy to molecularly optimize the cathode side of a proton exchange membrane fuel cell. This new cathode consists of a porous gold membrane with pores that function as gas diffusion ...
-
(2017-03-31)Department: Interdisciplinary Materials ScienceResearchers discovered the existence of non-coding RNA while unraveling the secrets of the human genome. Non-coding RNA molecules are never translated into proteins, yet they are highly abundant and serve critical functions ...
-
(2017-04-01)Department: Interdisciplinary Materials SciencePorous silicon, a nanostructured material formed by electrochemical etching of a silicon substrate, is an ideal candidate for constructing optical biosensors due to its large internal surface area, straightforward fabrication, ...
-
(Vanderbilt University. School of Engineering, 2002)
-
(Vanderbilt University. School of Engineering, 2002)