Browsing by Department "Biomedical Engineering"
Now showing items 21-40 of 349
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(2021-09-08)Department: Biomedical EngineeringNucleic acids have emerged as leading biomarkers for diagnostic technologies, as they allow for extremely specific discrimination of targets via base-pair binding. Overcoming the obstacles posed enzymes, non-enzymatic ...
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(2023-03-14)Department: Biomedical EngineeringDiagnostic tools available in high-income countries are often not available in lower- and middle-income countries (LMICs) due to the requirement of highly trained workers and expensive equipment. The COVID-19 pandemic ...
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(2023-06-01)Department: Biomedical EngineeringBone fragility is a widespread problem worldwide and the current clinical standard diagnosis method for evaluating bone fragility through Bone Mineral Density (BMD) is not always effective in predicting bone fracture risk. ...
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(2020-11-16)Department: Biomedical EngineeringThe spinal cord is a narrow, cylindrical structure responsible for rapidly transmitting electrical signals throughout the nervous system and is the primary sensorimotor pathway for the human body. Therefore, damage to the ...
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(2022-05-03)Department: Biomedical EngineeringFocused ultrasound (FUS) is a non-invasive therapeutic technology that can use ultrasonic energy to precisely target tissue deep inside the body without incisions or radiation. However, for the safety and credibility of ...
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(2016-06-01)Department: Biomedical EngineeringThe current standard for diagnosing fracture risk comprises measurements of bone mineral density (BMD), primarily by dual-energy X-ray absorptiometry (DXA). However, bone strength is affected by many factors other than ...
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(2007-04-10)Department: Biomedical EngineeringAs the rate of obesity increases in the western world, the interest in understanding the process of maintaining healthy body weight has become an increasingly important public health priority. Because physical activity is ...
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(2018-07-30)Department: Biomedical EngineeringFracture resistance of bone depends on the hierarchical organization of its constituents, primarily the organic matrix, mineral, and water, and as such, requires characterization at multiple length-scales. The extracellular ...
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(2023-06-30)Department: Biomedical EngineeringUltra-high field (UHF; 7 Tesla and higher) MRI provides enhanced sensitivity, contrast, and spatial resolution for neuroimaging exams than lower-field scanners. However, at the high Larmor frequencies of UHF scanners, ...
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(2011-12-13)Department: Biomedical EngineeringIn addition to the inherent chemical phase shift between different proton species, fat-water MRI k-space raw data are corrupted by several sources such as magnetic field inhomogeneity; chemical shift phase accumulated ...
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(2013-07-18)Department: Biomedical EngineeringPurpose: This study evaluates a new magnetic resonance imaging method for detecting calcium deposits, using their characteristic susceptibility effects, in practical conditions to provide insight into its clinical value ...
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(2006-04-18)Department: Biomedical EngineeringOur brains process and interpret sensory information in order to generate perceptions of the environment or motivate behavior. However, the underlying mechanisms by which salient stimulus qualities are represented ...
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(2021-03-22)Department: Biomedical EngineeringTemporal lobe epilepsy (TLE) is the most common form of epilepsy, a debilitating disease that affects 50 million people globally. In TLE, seizure onset is typically localized to an epileptogenic zone (EZ) in the mesial ...
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(2012-01-25)Department: Biomedical EngineeringThis project is concerned with in vitro assays of angiogenesis and how mechanical stimuli are controllably incorporated into them. The vascular explant assay is considered the most physiologically realistic in vitro ...
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(2021-10-13)Department: Biomedical EngineeringHelper T cell activity is dysregulated in a number of diseases with limited treatment options, including those associated with rheumatic autoimmunity. Phosphodiesterase 4 (PDE4) inhibition has the potential to enable ...
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(2017-03-27)Department: Biomedical EngineeringOsteoarthritis (OA) is a disease characterized by degradation of joints with the development of painful inflammation in the surrounding tissues. Post-traumatic osteoarthritis (PTOA) is OA that develops following a traumatic ...
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(2022-05-04)Department: Biomedical EngineeringFocused ultrasound (FUS) is a non-invasive and non-ionizing technology that can converge ultrasound beam at a point. FUS is currently FDA approved for ablating uterine fibroids, performing thalamotomies to relieve essential ...
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(2008-03-18)Department: Biomedical EngineeringPatient safety and emergency department functionality are compromised when inefficient coordination between hospital departments impedes ED patients’ access to inpatient cardiac care. The objective of this dissertation ...
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(2016-11-30)Department: Biomedical EngineeringNew therapies are needed to improve the mortality and morbidity of respiratory diseases, but few drug candidates for respiratory diseases are developed and only 3% drug candidates reach market (compared to 6-14% for other ...
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(2023-11-16)Department: Biomedical EngineeringGlaucoma is characterized by degeneration of the retinal nerve fiber layer (RNFL), which can be assessed by thickness measurement on optical coherence tomography (OCT) B-scans. However, detecting early-stage glaucoma remains ...