Macrophages have been proposed as a potential therapeutic target because of their central role in the progression of a number of debilitating diseases, such as cancer and cardiovascular diseases. However, macrophages are ...

One question guides this dissertation: what is a text? Answering this question pushes the boundaries of biblical studies, prompting more considerations: is a text limited to the words written on pages and inscribed in ...

Over the course of billions of years, nature has developed incredible materials on the nanoscale for the efficient conversion of solar energy into chemical energy. One of these materials, Photosystem I (PSI), functions as ...

Colorectal cancer is the second most lethal, non-cutaneous epithelial cancer in the United States. Metastasis contributes to the majority of cancer-related deaths in this disease. Metastasis closely resembles the ...

Genomic and transcriptomic analysis have revolutionized our understanding of many cancers. However, genomic understanding of thyroid cancer has lagged behind other tumors; currently, thyroid cancer management is largely ...

Chemical and biomedical sciences depend heavily on interaction assays, particularly those providing structural insights. This dissertation shows that free-solution, label-free studies report molecular conformation and ...

Current approaches to the synthesis of metal oxides generally require harsh conditions. In contrast, many biological processes can produce intricate metal oxide nanostructures under ambient conditions. For example, the ...

Ion mobility-mass spectrometry (IM-MS) applies a gas-phase separation on the basis of structure prior to the MS, enabling separation of different types of biomolecules based on their gas-phase packing efficiencies. For ...

In the research described, we developed methods and protocols for high-spatial resolution functional magnetic resonance imaging (fMRI) of cortical activity in the brains of anesthetized non-human primates with sub-millimeter ...