Browsing by Title
Now showing items 3642-3661 of 17411
-
(2013-07-17)Department: Biomedical EngineeringUnderstanding the contribution of individual mechanical stimuli to cardiovascular pathogenesis is critically important for understanding and treating cardiovascular disease, and microfluidic bioreactors are a useful tool ...
-
(2018-11-16)Department: Biomedical EngineeringT cell activity is dysregulated in a number of autoimmune diseases for which systemic lupus erythematosus is a prime example. Treatment options are limited and usually consist of overt immune suppression and compromised ...
-
(2005-12-16)Department: Biomedical EngineeringA persistent limitation to current and future anti-cancer therapies is an inability to deliver high levels of active agent throughout the entire target tumor tissue volume without adversely impacting normal tissues. ...
-
Development and Characterization of NMR and MRI Methods for Assessment of Tumor Oxygen Consumption (2012-10-08)Department: PhysicsA common feature of invasive cancers is that they have an upregulation of glucose metabolism and reduced oxygen utilization. The overall goal of this research was to develop a 17Oxygen MRI method to access this aberrant ...
-
(2015-07-15)Department: PharmacologyThe essential roles of glutamatergic signaling in both normal and impaired cognitive functioning have caused metabotropic glutamate (mGlu) receptors to become targets of interest for the treatment of psychiatric disorders. ...
-
(2019-04-08)Department: Biological SciencesOver the years, periodic innovations in fluorescence microscopic technologies have afforded researchers a more sophisticated understanding of the inner workings of the cell. These methods are valuable but drawbacks include ...
-
(2013-08-08)Department: Mechanical EngineeringExternally powered transradial prostheses have traditionally been limited to devices that are broad abstractions of the natural hand, possessing a single degree of freedom and having limited grasping capability. Enabled ...
-
(2007-07-31)Department: Biomedical InformaticsMass Spectrometry (MS) is emerging as a breakthrough mass-throughput technology believed to have powerful potential for producing clinical diagnostic and prognostic models and for identifying relevant disease biomarkers. ...
-
(2010-03-15)Department: Biomedical EngineeringWithin the last decade, magnetic resonance imaging (MRI) scanners with ultra-high magnetic field strengths of 7 Tesla and above have become available. While high magnetic fields provide theoretical improvements in the ...
-
(2016-11-17)Department: Biomedical EngineeringAdvanced neuroimaging techniques provide the possibility to non-invasively understand and monitor white matter during development and disease. While data from quantitative MRI techniques, such as multiexponential T2 (MET2) ...
-
(2019-03-19)Department: Biological SciencesThe Drosophila Giant Fiber (GF) circuit is a highly tractable set of neurons driving rapid escape behavior. The work presented here takes advantage of the large size and accessibility of these central neurons to study ...
-
(2010-12-17)Department: ChemistryChemistry Development and Improvement of Quantum Dot-Sensitized Solar Cell Architectures Shawn M. Rosson Thesis under the direction of Professor Sandra J. Rosenthal Nanostructured photovoltaic devices constructed ...
-
(2012-07-30)Department: ChemistryMonolayer-protected gold nanoparticles (AuNPs) have been the subject of much attention because of the simplicity of their synthesis, their stability, and the ease of functionalization via simple place-exchange reactions. ...
-
(2011-08-01)Department: PsychologyOne community sample (N = 607) of youths generated self-reported responses to body dissatisfaction, from which the Adolescent Responses to Body Dissatisfaction (ARBD) inventory was constructed. A second similar sample (N ...
-
(2019-07-18)Department: ChemistryThe manipulation and tailoring of crosslinked materials to engineer new materials with enhanced properties has been a growing field of interest in the past decade. Recent advances in light-mediated polymerizations such ...
-
(2014-03-25)Department: Civil EngineeringSystematic development of a new self-consolidating high-strength cementitious armor material, for use in protective construction against blast and ballistic impact, is presented. Multi-scale experimental methods are ...
-
Development and quantification of an atlas-based method for model-updated image-guided neurosurgery (2007-12-27)Department: Biomedical EngineeringThis dissertation covers research regarding the use of computational models during brain tumor resection therapies. Systematic studies have shown that the brain tissue shifts during tumor resection therapies and that current ...
-
(2012-04-17)Department: Mechanical EngineeringThis project designed, implemented, validated and tested a biofeedback system for wheelchair propulsion analysis which was named OptiPush Biofeedback System. The system includes an instrumented wheelchair wheel and biofeedback ...
-
(2022-07-15)Department: Chemical EngineeringTypically, the proton conductivity of a polymer electrolyte membrane (PEM) decreases when the relative humidity (RH) of the environment decreases or the temperature increases. This drawback significantly complicates the ...
-
(2014-12-01)Department: Interdisciplinary Materials ScienceThe favorable conductive properties of carbon nanotubes (CNTs) offer opportunities for constructing CNT-based nanocomposites with improved thermal conduction for a range of potential applications. Such lightweight composite ...