Given the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and chromatin structure, it is fitting that therapies targeting HDAC activities are now being explored ...

The majority of breast cancer patients receive radiation therapy. Although this treatment improves overall outcomes, patients with triple negative breast cancer (TNBC) have a significantly higher risk of distant and ...

The phagocytic nature and oxidative resiliency of macrophages not only allows them to function as innate immune cells but also to respond to specific tissue needs, such as iron homeostasis. MFehi ATMs are a subtype of ...

Antibiotic resistance is a growing global health threat. According to the CDC, nearly 2.8 million drug-resistant infections occur every year, killing 35,000 people annually. While research has focused on the acquisition ...

A critical step during gene expression is the directional export of nuclear messenger (m)RNA through nuclear pore complexes (NPCs) to the cytoplasm. During export, Gle1 in conjunction with inositol hexakisphosphate (IP6) ...

The capacity to read nonfiction text with understanding is of obvious and vital importance, yet many students struggle to do so. This randomized control trial extends previous research by contrasting the efficacy of a ...

Educators need strategies to build the communication skills of students learning to use aided augmentative and alternative communication (AAC), while also supporting their meaningful participation and interaction in inclusive ...

An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau ...