Browsing by Title
Now showing items 743-762 of 17440
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(2008-04-28)Department: Cancer BiologyWe have identified a novel signaling pathway, AKT/IKKα/VAV1, which induces endothelial cell survival and motility. Ang1/Tie2 and VEGF/VEGFR signaling activates Akt and induces cell survival. Akt and IKKƒÑ both induce ...
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(American Schools of Oriental Research, 1993)
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(2018-03-27)Department: Cancer BiologyMetastasis persists as a significant unsolved hurdle in cancer treatment, with greater than 90% of cancer-related deaths attributed to metastasis. In order for cells to successfully metastasize, they must dynamically ...
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(2016-11-28)Department: PharmacologyUnacceptable pharmacokinetics (PK) relating to aldehyde oxidase (AO) metabolism have resulted in clinical failure of several promising drug candidates, yet reliable and standardized methods to predict the human PK and ...
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(Vanderbilt University. Peabody College, 2012-06-14)This paper addresses the argument that algebra should be viewed as a civil right and mode for social justice. The framing question addressed is, “How and why is algebra a civil right?” The goal of the paper is to discuss ...
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(2018-11-27)Department: Computer ScienceLarge-scale medical imaging studies to date have predominantly leveraged in-house, laboratory-based or traditional grid computing resources for their computing needs, where the applications often use hierarchical data ...
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(2017-07-13)Department: Computer ScienceMarketing researchers and practitioners care about why and how products or services are adopted by consumers. The influential theory of innovation diffusion has been established for decades, but modeling and simulating the ...
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(2020-02-20)Department: Computer ScienceThe advent of the Internet of Things (IoT) has enabled smart applications, which provides near real-time and robust predictive data analytics. The backbone of these predictive analytics services is an underlying machine ...
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(2018-06-13)Department: Computer ScienceAn increasing number of Internet of Things (IoT) and other latency-sensitive applications are cloud-hosted. However, limitations in performance assurances from the cloud, and the longer and often unpredictable end-to-end ...
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(2016-11-22)Department: Computer ScienceOver the past decades, distributed computing paradigm has evolved from smaller and mostly homogeneous clusters to the current notion of ubiquitous computing, which consists of dynamic and heterogeneous resources in large ...
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(2015-04-06)Department: Computer ScienceThe Industrial Internet of Things (IIoT), which is a special class of Internet of Things (IoT), operates in large, distributed and dynamic environments comprising sensors all the way to large server clusters. IIoT is ...
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(2016-07-22)Department: Computer ScienceSoftware Defined Networking (SDN) has seen growing deployment in the large wired data center networks due to its advantages like better network manageability and higher-level abstractions. At the core of SDN is the separation ...
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(2021-03-11)Department: Electrical EngineeringThis dissertation improves the patient personalization of preoperative planning for a wide variety of surgical applications. These improvements are accomplished via the creation of several novel algorithms in two general ...
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(2018-04-17)Department: Computer ScienceTransportation infrastructure is a complex human cyber-physical system that is currently facing significant challenges in many communities around the world. The problem emanates from increased congestion, which results in ...
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(2008-12-06)Department: Biomedical InformaticsAlgorithms for discovery of a Markov boundary from data constitute one of the most important recent developments in machine learning, primarily because they offer a principled solution to the variable/feature selection ...
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(2018-08-22)Department: Computer ScienceDecision making in the presence of uncertainty received a major focus of traditional Artificial Intelligence (AI) research. In an adversarial environment with competing agents, this challenge is compounded by interdependence: ...