Browsing by Title
Now showing items 928-947 of 17382
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(Journal of Lipid Research, 2022-12)The cumulative exposure to apolipoprotein B (apoB)-containing lipoproteins in the blood during early adult life is a central determinant of atherosclerotic cardiovascular disease risk. To date, the patterns and rates of ...
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(2021-03-25)Department: ChemistryThe development of novel analytical methods and instrumentation has enabled the characterization of increasingly complex samples. In particular, mass spectrometry (MS) is a technique that has found broad application in the ...
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(Vanderbilt University, 2018)
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(2009-12-14)Department: Cell and Development BiologyBves is a transmembrane protein that influences cell migration, motility, and epithelial integrity through previously undefined mechanisms. In this dissertation, I present evidence that identifies the molecular basis for ...
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(2007-04-11)Department: Cell and Developmental BiologyThe work contained in this document describes the generation of new immunoreagents for Bves study, and our identification of a Bves-interacting protein. After generating new monoclonal antibodies to the Bves protein, I ...
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Analysis of Conflict of Interest Policies among Organizations Producing Clinical Practice Guidelines (PLoS One, 2021-04-30)Among organizations producing CPGs, COI policies frequently do not meet IOM standards, and organizations often violate their own policies. These shortcomings may undermine the public trust in and thus the utility of CPGs. ...
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(2015-02-11)Department: Microbiology and ImmunologyCoronaviruses are positive-sense RNA viruses that cause significant diseases in humans. Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) caused a pandemic in 2002-2003, and Middle East Respiratory Syndrome coronavirus ...
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(2008-03-31)Department: NeuroscienceThe primate visual system is highly interconnected and hierarchically organized. Three separate pathways, originating in the layers of the lateral geniculate nucleus (LGN), carry retinal information to primary visual cortex ...
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(2015-11-27)Department: Cell and Developmental BiologyCargo trafficking is the process by which proteins and lipid carriers are transported between intracellular compartments. Mutations in components of cargo trafficking machinery have been associated with a diverse collection ...
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(Environmental Law Reporter, 2020)The purpose of this article is to highlight the results of the ELPAR article selection process and to report on the environmental legal scholarship for the 2018-2019 academic year, including the number of environmental law ...
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(2008-12-06)Department: cell and developmental biologyA conserved biological feature of sexual reproduction in animals is that oocytes arrest in meiotic prophase and resume meiosis in response to extra-ovarian signals. In Caenorhabditis. elegans, a sperm-sensing mechanism ...
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(2007-10-03)Department: BiochemistryThe ErbB family of receptor tyrosine kinases regulates cell growth, differentiation, and tumorigenesis. This dissertation contains two independent studies of ErbB-1 and ErbB-4. In one study, the intracellular juxtamembrane ...
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(2022-03-23)Department: NeuroscienceThe vertebrate head is a complex structure consisting of diverse tissues that work cooperatively to perform a variety of craniofacial functions, such as speaking, breathing, processing and swallowing food, among others. ...
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(2019-03-27)Department: Mechanical EngineeringDesire for efficiency and weight reduction in engines has propelled the search for lightweight alloys which retain high mechanical strength at extreme temperatures. A novel aluminum cerium alloy system was developed as a ...
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(2005-06-07)Department: Chemical EngineeringTime-of-flight medium backscattering (TOF-MEBS) is a powerful analytical technique for characterizing high-k dielectric thin films and their interface with Si. The amount of information that can be obtained from backscattering ...
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(2006-05-18)Department: Microbiology and ImmunologyAutoimmune and atopic diseases are immune-mediated multigenic diseases. The work of this thesis tests the hypothesis of performing gene expression profiling using peripheral blood mononuclear cells as a common source to ...
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(2007-04-12)Department: Cell and Developmental BiologyIn eukaryotes, all nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs). These giant proteinaceous structures are embedded in the nuclear envelope where the outer nuclear membrane and inner nuclear ...
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(2012-08-06)Department: Cell and Developmental BiologyMesothelium is a simple squamous epithelium that forms the surface layer of all coelomic cavities and organs. Despite its widespread localization, mesothelial development has been studied almost exclusively in the heart. ...
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(2008-07-16)Department: Microbiology and ImmunologyThe á2â1 integrin is expressed on many cell types throughout the immune system. Expression of the á2â1 integrin on mast cells is required for the early innate immune response to Listeria monocytogenes. Interaction between ...
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(2004-04-09)Department: Chemical EngineeringMethylglyoxal (MG) is a toxic compound which is produced in cells as a byproduct of glycolysis. Recently, the compound has been suggested as a damaging agent in batch cultures of production cell lines. In the current ...