Browsing by Title
Now showing items 940-959 of 17427
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(2007-10-03)Department: BiochemistryThe ErbB family of receptor tyrosine kinases regulates cell growth, differentiation, and tumorigenesis. This dissertation contains two independent studies of ErbB-1 and ErbB-4. In one study, the intracellular juxtamembrane ...
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(2022-03-23)Department: NeuroscienceThe vertebrate head is a complex structure consisting of diverse tissues that work cooperatively to perform a variety of craniofacial functions, such as speaking, breathing, processing and swallowing food, among others. ...
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(2019-03-27)Department: Mechanical EngineeringDesire for efficiency and weight reduction in engines has propelled the search for lightweight alloys which retain high mechanical strength at extreme temperatures. A novel aluminum cerium alloy system was developed as a ...
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(2005-06-07)Department: Chemical EngineeringTime-of-flight medium backscattering (TOF-MEBS) is a powerful analytical technique for characterizing high-k dielectric thin films and their interface with Si. The amount of information that can be obtained from backscattering ...
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(2006-05-18)Department: Microbiology and ImmunologyAutoimmune and atopic diseases are immune-mediated multigenic diseases. The work of this thesis tests the hypothesis of performing gene expression profiling using peripheral blood mononuclear cells as a common source to ...
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(2007-04-12)Department: Cell and Developmental BiologyIn eukaryotes, all nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs). These giant proteinaceous structures are embedded in the nuclear envelope where the outer nuclear membrane and inner nuclear ...
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(2012-08-06)Department: Cell and Developmental BiologyMesothelium is a simple squamous epithelium that forms the surface layer of all coelomic cavities and organs. Despite its widespread localization, mesothelial development has been studied almost exclusively in the heart. ...
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(2008-07-16)Department: Microbiology and ImmunologyThe á2â1 integrin is expressed on many cell types throughout the immune system. Expression of the á2â1 integrin on mast cells is required for the early innate immune response to Listeria monocytogenes. Interaction between ...
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(2004-04-09)Department: Chemical EngineeringMethylglyoxal (MG) is a toxic compound which is produced in cells as a byproduct of glycolysis. Recently, the compound has been suggested as a damaging agent in batch cultures of production cell lines. In the current ...
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(2012-07-24)Department: PhysicsCoal combustion residues from coal fired power plants are advantageous for use in building and construction materials. These by-products contain trace quantities of natural radionuclides from the uranium and thorium series, ...
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(2007-06-21)Department: PathologyThis project is focused on understanding the molecular mechanisms of prostate tumor initiation due the loss of the tumor suppressor gene Nkx3.1. Here, we examined the dosage-sensitive and stochastic target gene regulation ...
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(2010-03-02)Department: Microbiology and ImmunologyCoronaviruses belong to a family of enveloped, positive-strand RNA viruses that cause a multitude of devastating diseases in both animals and humans. Like other positive-strand RNA viruses, coronaviruses utilize several ...
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Analysis of parameter variation impact on the single event response in sub-100nm CMOS storage cells (2012-04-21)Department: Electrical EngineeringCurrent deep sub-micron technologies are particularly susceptible to single events. The challenge derives from a conglomeration of effects that affect circuits’ radiation response. For instance, decreasing device size ...
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(2007-10-26)Department: Biological SciencesThe cerebellum, which forms from anterior hindbrain, coordinates motor movements and balance. Sensory input from the periphery is relayed and modulated by cerebellar interneurons, which are organized into layers. The ...
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Analysis of power spectrum density of male speech as indicators for high risk and depressed decision (2017-01-09)Department: Electrical EngineeringAssessment of a patients risk of committing suicide is important in order for them to be able to receive early hospitalization. The two critical mental states that may arouse much confusion to the clinicians are the high ...
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(2023-07-17)Department: PsychologyProcess data can provide researchers with valuable insights into students’ behaviors during reading and while completing assessments. However, the complex and messy nature of process data makes the extraction of useful ...
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(2003-04-18)Department: Electrical EngineeringNumerical process and device simulation tools are used in this work to analyze the physical mechanisms that contribute to catastrophic failure of power Schottky diodes exposed to an electron beam pulse. Simulations suggest ...
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(2011-07-11)Department: ChemistryNew highly sensitive strategies for the analysis of proteins from selected cell populations in morphologically complex tissues have been developed. These workflows combine the single cell specificity of laser capture ...
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(2017-06-19)Department: MathematicsA fundamental problem in signal processing called signal reconstruction, or signal recovery, is the determination of a signal from a sequence of samples obtained from the signal. The sampling process can be viewed as ...
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(2009-07-19)Department: Biological SciencesDuring spinal cord development, precursor cells transition from proliferative divisions to differentiative divisions. Traditionally proliferative divisions, which increase cell numbers, are thought to be symmetric, whereas ...