Browsing by Author "Aaron B. Bowman"
Now showing items 1-7 of 7
-
Tidball, Andrew Martin (2014-09-29)Department: NeuroscienceThe essential micronutrient manganese is enriched in brain, especially the basal ganglia. We sought to identify neuronal signaling pathways responsive to neurologically relevant manganese levels, as previous data suggested ...
-
Vollbrecht, Peter John (2014-04-17)Department: NeuroscienceBoth dopamine and glutamate are critically involved in cognitive processes such as working memory. Evidence has demonstrated that manipulation of either neurotransmitter can lead to alterations in the other. Astrocytes, ...
-
Kraemer, Bradley Rhoads (2014-08-28)Department: NeuroscienceThe p75 Neurotrophin Receptor (p75NTR) is a critical regulator of axon pruning and apoptosis during neurodevelopment. Because the receptor has also been associated with many injurious or pathological conditions involving ...
-
Bylund, Jeffery B. (2017-04-05)Department: PharmacologyHeart development depends on coordinated proliferation and differentiation of cardiac progenitor cells, but how the two processes are synchronized is not well understood. The data herein show that the secreted BMP antagonist ...
-
Madison, Jennifer Lea (2011-07-28)Department: PharmacologyHuntington’s disease is a fatal autosomal dominant neurodegenerative disease caused by an expansion of CAG repeats in the DNA of the Huntingtin gene. The length of the repeat is inversely related to the age of disease ...
-
Kumar, Kevin Krishan (2014-08-29)Department: NeuroscienceManganese (Mn) is both an essential biological cofactor and neurotoxicant. Disruption of Mn biology in the basal ganglia has been implicated in the pathogenesis of neurodegenerative disorders, such as parkinsonism and ...
-
Juttukonda, Lillian Johnson (2017-08-28)Department: Microbiology and ImmunologyBacterial pathogens must acquire nutrients from the host during infection. The transition metal manganese (Mn) is an essential nutrient for both bacteria and vertebrates. Molecular mechanisms by which the opportunistic ...