Browsing by Author "Anna Means"

Now showing items 1-6 of 6

    • Analysis of the mRNA-binding protein Nab2 during the nuclear export mechanism 
      Carmody, Sean Robert (2010-12-04)
      Department: Cell and Developmental Biology
      This project is concerned with understanding the role of the mRNA-binding protein Nab2 in the process of nuclear mRNA export. In this dissertation I characterize changes that occur to Nab2’s structure and localization ...
    • Regulation of gene expression in the embryonic pancreas by Oc1 and its impact on postnatal function 
      Kropp, Peter Allerton (2018-01-03)
      Department: Molecular Physiology and Biophysics
      The pancreas is a dual function organ contributing to both blood glucose homeostasis and digestion. These functions are carried out by the endocrine and exocrine compartments of the pancreas, respectively, which derive ...
    • Shh signaling in limb development 
      Liu, Jiang (2013-02-19)
      Department: Cell and Developmental Biology
      Sonic hedgehog (Shh), a secreted signaling molecule, is generated from the posterior limb margin and essential in regulating anterior-posterior (A-P) patterning as well as growth and differentiation of limb mesenchyme. ...
    • The Role of Connective Tissue Growth Factor in Islet Morphogenesis and Beta Cell Proliferation 
      Guney, Michelle Aylin (2011-03-29)
      Department: Molecular Physiology and Biophysics
      Pancreatic beta cells are the only cell type in the body that can produce insulin, a hormone required for maintaining glucose homeostasis. Type 1 and type 2 diabetes result from an absolute or relative reduction in functional ...
    • The Role of FoxM1 in Pancreatic Beta Cell Mass Regeneration and Expansion 
      Misfeldt, Amanda Ackermann (2008-09-29)
      Department: Molecular Physiology and Biophysics
      MOLECULAR PHYSIOLOGY AND BIOPHYSICS THE ROLE OF FOXM1 IN PANCREATIC BETA CELL MASS REGENERATION AND EXPANSION AMANDA ACKERMANN MISFELDT Dissertation under the direction of Maureen Gannon, Ph.D. The size of an organism’s ...
    • The trafficking of amphiregulin in polarized epithelial cells 
      Gephart, Jonathan David (2011-07-29)
      Department: Cell and Developmental Biology
      Epithelial cells establish apical and basolateral (BL) membranes with distinct protein and lipid compositions. To achieve this spatial asymmetry, the cell utilizes a variety of mechanisms for differential sorting, delivery ...