Browsing by Author "Antonis Hatzopoulos"
Now showing items 1-7 of 7
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Misfeldt, Andrew Michael (2008-12-30)Department: Cell and Developmental BiologyIdentification of multipotent cardiac progenitors has provided fresh insight into the mechanisms of myocardial lineage specification, yet has done little to clarify the origin of the endocardium. Despite its essential role ...
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Aisagbonhi, Omonigho Augustina (2010-09-21)Department: Cell and Developmental BiologyThis dissertation project was aimed at elucidating cellular and molecular responses to myocardial infarction. Our work identified canonical wnt signaling as a molecular pathway that is induced in the healing (granulation ...
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Schroer, Alison Koelle (2016-11-22)Department: Biomedical EngineeringHeart disease is a leading cause of death worldwide, and many cardiac conditions that contribute to high morbidity and mortality are characterized by tissue fibrosis and maladaptive remodeling. Build-up of extracellular ...
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Alfaro, Maria Paula (2011-04-04)Department: PathologyBone marrow-derived mesenchymal stem cells (MSCs) are an attractive candidate for cell-mediated wound repair. Due to their plasticity, MSCs have been utilized in several preclinical and clinical trials of tissue regeneration. ...
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Riley, Kimberly Ann Gooding (2015-03-25)Department: Cell and Developmental BiologyAs diabetes continues to affect millions of people within the United States, identification of novel factors that may enhance beta-cell proliferation and mass regeneration in vivo is critical. Our lab previously demonstrated ...
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DeLaughter, Daniel Morris (2013-06-10)Department: Cell and Developmental BiologyEpithelial-to-Mesenchymal Transformation (EMT) is an important process in development, and occurs during key steps in both valvular and coronary vessel development. This dissertation uses transcriptional profiling strategies ...
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Boone, David Nelson (2011-04-08)Department: Cell and Developmental Biologyc-Myc is frequently deregulated in human cancers. While deregulated c-Myc leads to tumor growth, it also triggers apoptosis in partnership with tumor suppressors such as ARF and p53. Apoptosis induced by c-Myc is a ...