Browsing by Author "Bih-Hwa Shieh"

Now showing items 1-4 of 4

    • A drosophila model of cellular and molecular mechanisms of fragile x syndrome. 
      Pan, Luyuan (2007-12-17)
      Department: Biological Sciences
      Fragile X Syndrome (FXS) is the most common form of inherited mental retardation. In this thesis, I describe my work using a Drosophila model to study cellular, molecular and genetic mechanisms that underlie the cognitive ...
    • Regulation of the CaMKIV/PP2A Signaling Module 
      Reece, Kelie M'liss (2010-02-02)
      Department: Pharmacology
      Calcium/calmodulin-dependent protein kinase IV (CaMKIV) is a serine/threonine kinase that plays a crucial role in the control of synaptic plasticity and T cell maturation. Activation of CaMKIV requires Ca2+/calmodulin ...
    • Regulation of the neuronal K+-Cl- cotransporter KCC2 by protein associated with MYC 
      Garbarini, Nicole Jodela (2008-04-28)
      Department: Neuroscience
      The neuron-specific electroneutral potassium (K+) and chloride (Cl-) cotransporter, KCC2, is a key regulator of neuronal Cl-. KCC2 has been shown to play a critical role in controlling neuronal excitability, yet little ...
    • Regulation of the TRP calcium channel by eye-PKC in Drosophila 
      Popescu, Daniela Catalina (2006-11-27)
      Department: Pharmacology
      The transient receptor potential (TRP) ion channels are implicated in diverse physiological processes, however their regulatory mechanisms remain obscure. In Drosophila, TRP is a calcium channel mediating the light-dependent ...