Browsing by Author "Charles Lin"
Now showing items 1-5 of 5
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DeBusk, Laura M (2008-04-28)Department: Cancer BiologyWe have identified a novel signaling pathway, AKT/IKKα/VAV1, which induces endothelial cell survival and motility. Ang1/Tie2 and VEGF/VEGFR signaling activates Akt and induces cell survival. Akt and IKKƒÑ both induce ...
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Mackert, John Rodway (2012-12-14)Department: Cell and Developmental BiologyMyeloid-derived suppressor cells (MDSCs) play an important role in cancer progression. Elucidating the mechanisms involved in the expansion and function of these cells is important in the fight against cancer. A microarray ...
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Vaught, David Bryan (2011-04-18)Department: Cancer BiologyEph receptor tyrosine kinases are membrane bound receptors often expressed by normal epithelial cells but are frequently overexpressed in many human cancers. Of the many Eph receptors, EphA2 is present at low levels in ...
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Boelte, Kimberly Covington (2011-03-29)Department: Cancer BiologyMyeloid derived suppressor cells (MDSCs) play an important role in cancer progression, and elucidating the mechanisms involved in the accumulation and function of these cells is important. Preliminary data indicated that ...
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Woo, Kel Vin (2010-07-12)Department: Cell and Developmental BiologyAlthough it is known that the response of endothelial cells to atherogenic disturbed flow is distinct from that elicited by non-atherogenic laminar flow, the mechanisms involved are poorly understood. Observing that ...