Browsing by Author "Christopher B. Brown"
Now showing items 1-6 of 6
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Bylund, Jeffery B. (2017-04-05)Department: PharmacologyHeart development depends on coordinated proliferation and differentiation of cardiac progenitor cells, but how the two processes are synchronized is not well understood. The data herein show that the secreted BMP antagonist ...
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Fioret, Bryan Adam (2014-07-03)Department: PharmacologyCardiac tissue undergoes renewal with low rates. Although resident stem cell populations have been identified to support cardiomyocyte turnover, the source of the cardiac stem cells and their niche remain elusive. Using ...
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Barnett, Joshua McAlister (2011-08-08)Department: PharmacologyThe field of research into endothelial progenitor cells is complex and difficult to interpret. There are a number different investigators working on specific subpopulations that are isolated in unique ways using unique ...
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Ciampa, Erin Julia (2011-03-14)Department: PharmacologyKCNE4 is a potassium channel modulating protein that can dramatically inhibit distinct potassium currents, but we lack a clear understanding its mechanism for doing so and its physiologic significance. In this project we ...
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Sewell-Loftin, Mary Kathryn (2014-04-01)Department: Biomedical EngineeringNearly 300,000 heart valve (HV) replacement surgeries are performed annually, including both pediatric patients with valvular defects and elderly patients suffering from degenerative or calcific valve diseases. Worldwide, ...
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Chen, Joseph (2015-03-26)Department: Biomedical EngineeringCalcific aortic valve disease (CAVD) is the predominant valvular disease in the developed world, affecting over five million individuals in the United States alone and manifests itself as a progressive disease resulting ...