Browsing by Author "Christopher Williams"
Now showing items 1-5 of 5
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Barrett, Caitlyn Whitten (2013-09-23)Department: Cancer BiologyInflammatory bowel disease (IBD), which affects 1 in 600 Americans, is characterized by severe and chronic inflammation, a known contributor to cancer. As such, the risk for cancer is increased in patients with IBD compared ...
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Gallant, Jean-Nicolas (2017-04-12)Department: Cancer BiologyLung cancer is the leading cause of cancer deaths worldwide. More than 40% of lung cancers are classified as lung adenocarcinoma (LUAD), which is defined by pathological characteristics. Oncogenic mutations in the epidermal ...
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Wells, Christina Elizabeth (2013-04-09)Department: BiochemistryGiven the fundamental roles of histone deacetylases (HDACs) in the regulation of DNA repair, replication, transcription and chromatin structure, it is fitting that therapies targeting HDAC activities are now being explored ...
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Andrews, Omozusi E. (2014-07-28)Department: Biological SciencesSmall noncoding RNAs including miRNAs and siRNAs play significant roles in gene regulation via the mechanism of RNA interference (RNAi) and have been exploited to conduct loss-of-function studies. The discovery that these ...
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Parang, Bobak (2015-07-14)Department: Cancer BiologyIntestinal homeostasis relies on complex interactions between the intestinal epithelium, microbiota, and host immune system, all of which cooperate to maintain homeostasis in an environment colonized and challenged by an ...