Browsing by Author "Dan M. Roden"
Now showing items 1-6 of 6
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Smith, Joshua Carl (2016-04-09)Department: Biomedical InformaticsUnrecognized adverse drug effects (ADEs) pose a serious clinical problem. They negatively affect patients’ health and quality of life, generate preventable emergency department visits and hospital admissions, and increase ...
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Bersell, Kevin Richard (2016-11-03)Department: PharmacologyThe application of genome science to inherited heart disease requires accurate genetic evaluation and understanding of physiologic resulting from genetic variation. Using a Long QT syndrome phenotype that is very suggestive ...
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McElroy, Jude James (2013-07-17)Department: Human GeneticsPreterm birth (PTB), defined as live birth before 37 weeks’ completed gestation, is the leading cause of infant mortality worldwide. Despite this major public health concern, little is known about the pathogenesis of PTB. ...
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Feaster, Tromondae Kenta (2015-11-18)Department: PharmacologyHuman induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) have the potential to be an important tool for cardiovascular disease modeling, pre-clinical cardiotoxicity evaluation, and drug discovery. However, ...
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Campbell, Courtney Michelle (2013-08-06)Department: PharmacologyAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia in adults. The discovery of mutations in familial AF illustrated the contribution of specific genetic factors to AF susceptibility and suggested ...
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McCall, Abraham Scott (2015-07-23)Department: PharmacologyBasement membranes are a distinct form of extracellular matrix responsible for signal transduction and mechanical integrity throughout development, in mature tissues, and during wound healing. The collagen IV scaffold of ...