Browsing by Author "Xiangli Yang"
Now showing items 1-5 of 5
-
Clendenning, Dawn Elizabeth (2012-04-26)Department: Human GeneticsHUMAN GENETICS DETERMINING THE ROLE OF GROWTH DIFFERENTIATION FACTOR-6 (GDF6) IN THE DEVELOPMENT OF THE CORONAL SUTURE DAWN ELIZABETH CLENDENNING Dissertation under the direction of Professor Douglas P. Mortlock Growth ...
-
Broeckelmann, Eva Marie (2013-04-16)Department: Interdisciplinary Studies: Human GeneticsA member of the TGF-â superfamily of cytokines, BMP2 not only plays a critical role in pattern formation and morphogenesis during early embryonic development, but also promotes osteoblast differentiation and bone formation, ...
-
Wang, Weiguang (2011-07-29)Department: PharmacologyActivating transcription factor 4 (Atf4) is a leucine zip transcription factor. Atf4 mutant (Atf4-/-) mice show severe low bone mass and short stature phenotype. Atf4 is expressed in growth plate chondrocytes. Atf4-/- ...
-
Karolak, Matthew Ross (2015-07-17)Department: PharmacologyNeurofibromatosis type 1 (NF1) is the most common autosomal dominant genetic disorder occurring in 1 of every 3500 live births. NF1 is caused by loss-of-function mutations in NF1, the gene encoding the Ras-GAP neurofibromin. ...
-
Lian, Na (2011-04-14)Department: PharmacologyThis project is concerned with mechanisms underlying osteoblast differentiation, a critical process during bone remodeling and repair. In this dissertation I explored novel regulators for osteoblast differentiation by ...