Browsing by Subject "Autoimmunity"

Now showing items 1-3 of 3

    • Characterization of an Autoimmune Gene Expression Signature 
      Maas, Kevin Henry (2006-08-09)
      Department: Microbiology and Immunology
      MICROBIOLOGY AND IMMUNOLOGY CHARACTERIZATION OF AN AUTOIMMUNE GENE EXPRESSION SIGNATURE KEVIN MAAS Dissertation under the direction of Professor Thomas Aune Autoimmune diseases affect approximately 5% of the human ...
    • Dysregulated T-B Lymphocyte Collaboration in Autoimmunity Poses a Barrier to Transplant Tolerance 
      Stocks, Blair Taylor (2016-07-24)
      Department: Microbiology and Immunology
      Achieving transplant tolerance in the autoimmune environment will require targeting multiple immunologic dysregulations in T-B lymphocyte collaboration that drive the aggressive anti-graft response. At a biologic level, ...
    • Peripheral Tolerance in Anti-Insulin B Lymphocytes 
      Williams, Jonathan Murphy (2015-11-09)
      Department: Microbiology and Immunology
      Overall, these studies examine how peripheral tolerance is governed for autoreactive B lymphocytes that bind the relevant autoAg, insulin. CSR-competent anti-insulin B cells enter mature compartments but are anergic, ...